Allelic differences in the relationship between proteasome activity and MHC class I peptide loading.
(1998)
Journal Article
Benham, A., Grommé, M., & Neefjes, J. (1998). Allelic differences in the relationship between proteasome activity and MHC class I peptide loading. The Journal of Immunology, 161(1), 83-89
MHC class I molecules are cell surface glycoproteins that play a pivotal role in the response to intracellular pathogens. The loading of MHC class I molecules with antigenic substrates takes place in the endoplasmic reticulum. This requires a functio... Read More about Allelic differences in the relationship between proteasome activity and MHC class I peptide loading..