All Outputs (994)

Post-16 students’ experience of practical science during the COVID-19 pandemic and the impact on students’ self-efficacy in practical work (2024)
Journal Article
Cramman, H., Arenas, B., Awais, R., Balaban, C., Cropper, C., Dennis, F., Finch, K., Gray, H., Hall, A., Kitchen, G., Norman, K., O’Driscoll, L., Petts, P., Petri, S., Robson, J., Rosenburgh, A., Shields, L., Swift, G. P., & Vaughan, H. (2024). Post-16 students’ experience of practical science during the COVID-19 pandemic and the impact on students’ self-efficacy in practical work. Enhancing Teaching and Learning in Higher Education, 2, 39-69. https://doi.org/10.62512/etlhe.14

This paper presents the findings from a detailed study investigating UK undergraduate students’ experience of practical science in their post-16 studies during the COVID-19 pandemic. It also examines their perceived confidence and preparedness in rel... Read More about Post-16 students’ experience of practical science during the COVID-19 pandemic and the impact on students’ self-efficacy in practical work.

Modulation of the Nogo signaling pathway to overcome amyloid-β-mediated neurite inhibition in human pluripotent stem cell-derived neurites. (2024)
Journal Article
Goncalves, K., & Przyborski, S. (2025). Modulation of the Nogo signaling pathway to overcome amyloid-β-mediated neurite inhibition in human pluripotent stem cell-derived neurites. Neural Regeneration Research, 20(9), 2645-2654. https://doi.org/10.4103/NRR.NRR-D-23-01628

Neuronal cell death and the loss of connectivity are two of the primary pathological mechanisms underlying Alzheimer's disease. The accumulation of amyloid-β peptides, a key hallmark of Alzheimer's disease, is believed to induce neuritic abnormalitie... Read More about Modulation of the Nogo signaling pathway to overcome amyloid-β-mediated neurite inhibition in human pluripotent stem cell-derived neurites..

Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule. (2024)
Journal Article
Kelly, G., Kataura, T., Panek, J., Ma, G., Salmonowicz, H., Davis, A., Kendall, H., Brookes, C., Ayine-Tora, D. M., Banks, P., Nelson, G., Dobby, L., Pitrez, P. R., Booth, L., Costello, L., Richardson, G. D., Lovat, P., Przyborski, S., Ferreira, L., Greaves, L., …Korolchuk, V. I. (2024). Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule. Developmental Cell, 59(15), 1924-1939. https://doi.org/10.1016/j.devcel.2024.04.020

Selective degradation of damaged mitochondria by autophagy (mitophagy) is proposed to play an important role in cellular homeostasis. However, the molecular mechanisms and the requirement of mitochondrial quality control by mitophagy for cellular phy... Read More about Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule..

Understanding health service utilisation patterns for care home residents during the COVID-19 pandemic using routinely collected healthcare data (2024)
Journal Article
Garner, A., Preston, N., Caiado, C., Stubington, E., Hanratty, B., Limb, J., …Knight, J. (2024). Understanding health service utilisation patterns for care home residents during the COVID-19 pandemic using routinely collected healthcare data. BMC Geriatrics, 24(1), Article 449. https://doi.org/10.1186/s12877-024-05062-6

Background: Healthcare in care homes during the COVID-19 pandemic required a balance, providing treatment while minimising exposure risk. Policy for how residents should receive care changed rapidly throughout the pandemic. A lack of accessible data... Read More about Understanding health service utilisation patterns for care home residents during the COVID-19 pandemic using routinely collected healthcare data.

The impact of digital technology in care homes on unplanned secondary care usage and associated costs. (2024)
Journal Article
Garner, A., Lewis, J., Dixon, S., Preston, N., Caiado, C. C. S., Hanratty, B., …Mason, S. M. (2024). The impact of digital technology in care homes on unplanned secondary care usage and associated costs. Age and Ageing, 53(2), 1-7. https://doi.org/10.1093/ageing/afae004

Background
A substantial number of Emergency Department (ED) attendances by care home residents are potentially avoidable. Health Call Digital Care Homes is an app-based technology that aims to streamline residents’ care by recording their observati... Read More about The impact of digital technology in care homes on unplanned secondary care usage and associated costs..

Impact of the Physical Cellular Microenvironment on the Structure and Function of a Model Hepatocyte Cell Line for Drug Toxicity Applications (2023)
Journal Article
Allcock, B., Wei, W., Goncalves, K., Hoyle, H., Robert, A., Quelch-Cliffe, R., …Przyborski, S. (2023). Impact of the Physical Cellular Microenvironment on the Structure and Function of a Model Hepatocyte Cell Line for Drug Toxicity Applications. Cells, 12(19), Article 2408. https://doi.org/10.3390/cells12192408

It is widely recognised that cells respond to their microenvironment, which has implications for cell culture practices. Growth cues provided by 2D cell culture substrates are far removed from native 3D tissue structure in vivo. Geometry is one of ma... Read More about Impact of the Physical Cellular Microenvironment on the Structure and Function of a Model Hepatocyte Cell Line for Drug Toxicity Applications.

Using deep learning to analyze the psychological effects of COVID-19 (2023)
Journal Article
Almeqren, M. A., Almegren, M., Alhayan, F., Cristea, A. I., & Pennington, D. R. (2023). Using deep learning to analyze the psychological effects of COVID-19. Frontiers in Psychology, 14, Article 962854. https://doi.org/10.3389/fpsyg.2023.962854

Problem: Sentiment Analysis (SA) automates the classification of the sentiment of people’s attitudes, feelings or reviews employing natural language processing (NLP) and computational approaches. Deep learning has recently demonstrated remarkable suc... Read More about Using deep learning to analyze the psychological effects of COVID-19.

The engage taxonomy: SDT-based measurable engagement indicators for MOOCs and their evaluation (2023)
Journal Article
Cristea, A. I., Alamri, A., Alshehri, M., Dwan Pereira, F., Toda, A. M., Harada T. de Oliveira, E., & Stewart, C. (2024). The engage taxonomy: SDT-based measurable engagement indicators for MOOCs and their evaluation. User Modeling and User-Adapted Interaction, 34(2), 323-374. https://doi.org/10.1007/s11257-023-09374-x

Massive Online Open Course (MOOC) platforms are considered a distinctive way to deliver a modern educational experience, open to a worldwide public. However, student engagement in MOOCs is a less explored area, although it is known that MOOCs suffer... Read More about The engage taxonomy: SDT-based measurable engagement indicators for MOOCs and their evaluation.

Feral American mink (Neogale vison) continues to expand its European range: time to harmonize population monitoring and coordinate control (2023)
Journal Article
Vada, R., Illanas, S., Acevedo, P., Adriaens, T., Apollonio, M., Belova, O., Blanco-Aguiar, J., Csányi, S., Body, G., G.Fernández-De-Mera, I., Ferroglio, E., A.Jansen, P., M.Jeschke, J., Keuling, O., Palazón, S., Plis, K., Podgórski, T., Rickowski, F., Scandura, M., Shakun, V., …Vicente, J. (2023). Feral American mink (Neogale vison) continues to expand its European range: time to harmonize population monitoring and coordinate control. Mammal Review, 53(3), 158-176. https://doi.org/10.1111/mam.12315

The MillenniumTNG Project: Intrinsic alignments of galaxies and halos (2023)
Journal Article
Delgado, A. M., Hadzhiyska, B., Bose, S., Springel, V., Hernquist, L., Barrera, M., Pakmor, R., Ferlito, F., Kannan, R., Hernández-Aguayo, C., White, S. D., & Frenk, C. (2023). The MillenniumTNG Project: Intrinsic alignments of galaxies and halos. Monthly Notices of the Royal Astronomical Society, 523(4), 5899–5914. https://doi.org/10.1093/mnras/stad1781

The intrinsic alignment (IA) of observed galaxy shapes with the underlying cosmic web is a source of contamination in weak lensing surveys. Sensitive methods to identify the IA signal will therefore need to be included in the upcoming weak lensing an... Read More about The MillenniumTNG Project: Intrinsic alignments of galaxies and halos.

A camera trap method for estimating target densities of grey squirrels to inform wildlife management applications (2023)
Journal Article
Beatham, S., Stephens, P., Coats, J., Phillips, J., & Massei, G. (2023). A camera trap method for estimating target densities of grey squirrels to inform wildlife management applications. Frontiers in Ecology and Evolution, 11, Article 1096321. https://doi.org/10.3389/fevo.2023.1096321

Effective wildlife population management requires an understanding of the abundance of the target species. In the UK, the increase in numbers and range of the non-native invasive grey squirrel Sciurus carolinensis poses a substantial threat to the ex... Read More about A camera trap method for estimating target densities of grey squirrels to inform wildlife management applications.

Drivers of the changing abundance of European birds at two spatial scales (2023)
Journal Article
Gregory, R., Eaton, M. A., Burfield, I., Grice, P. V., Howard, C., Klvaňová, A., Stephens, P., Willis, S., Woodward, I. D., & Burns, F. (2023). Drivers of the changing abundance of European birds at two spatial scales. Philosophical Transactions of the Royal Society B: Biological Sciences, 378(1881), Article 20220198. https://doi.org/10.1098/rstb.2022.0198

Detecting biodiversity change and identifying its causes is challenging because biodiversity is multifaceted and temporal data often contain bias. Here, we model temporal change in species' abundance and biomass by using extensive data describing the... Read More about Drivers of the changing abundance of European birds at two spatial scales.

Language as a latent sequence: Deep latent variable models for semi-supervised paraphrase generation (2023)
Journal Article
Yu, J., Cristea, A. I., Harit, A., Sun, Z., Aduragba, O. T., Shi, L., & Al Moubayed, N. (2023). Language as a latent sequence: Deep latent variable models for semi-supervised paraphrase generation. AI open, 4, 19-32. https://doi.org/10.1016/j.aiopen.2023.05.001

This paper explores deep latent variable models for semi-supervised paraphrase generation, where the missing target pair for unlabelled data is modelled as a latent paraphrase sequence. We present a novel unsupervised model named variational sequence... Read More about Language as a latent sequence: Deep latent variable models for semi-supervised paraphrase generation.

Remote monitoring of short-term body mass variation in savanna ungulates (2023)
Journal Article
Fuentes-Allende, N., Stephens, P., MacTavish, L., MacTavish, D., & Willis, S. (online). Remote monitoring of short-term body mass variation in savanna ungulates. Remote Sensing in Ecology and Conservation, 9(5), 707-723. https://doi.org/10.1002/rse2.338

Large herbivores in seasonal environments often experience mass variation due to temporal changes in the availability of critical resources like water and forage, as well as due to breeding events. Yet the documentation of mass variation in mammals o... Read More about Remote monitoring of short-term body mass variation in savanna ungulates.

Generation of a novel three-dimensional scaffold-based model of the bovine endometrium (2023)
Journal Article
Díez, M., Przyborski, S., del Cerro, A., Alonso-Guervós, M., Iglesias-Cabo, T., Carrocera, S., …Muñoz, M. (2023). Generation of a novel three-dimensional scaffold-based model of the bovine endometrium. Veterinary Research Communications, 47(3), 1721-1733. https://doi.org/10.1007/s11259-023-10130-0

Bovine in vitro endometrial models that resemble tissue function in vivo are needed to study infertility, long-term uterine alterations induced by pathogens and impact of endocrine disruptor chemicals on reproductive function and other reproductive s... Read More about Generation of a novel three-dimensional scaffold-based model of the bovine endometrium.

Removing Human Bottlenecks in Bird Classification Using Camera Trap Images and Deep Learning (2023)
Journal Article
Chalmers, C., Fergus, P., Wich, S., Longmore, S., Walsh, N., Stephens, P., Sutherland, C., Matthews, N., Mudde, J., & Nuseibeh, A. (2023). Removing Human Bottlenecks in Bird Classification Using Camera Trap Images and Deep Learning. Remote Sensing, 15(10), Article 2638. https://doi.org/10.3390/rs15102638

Birds are important indicators for monitoring both biodiversity and habitat health; they also play a crucial role in ecosystem management. Declines in bird populations can result in reduced ecosystem services, including seed dispersal, pollination an... Read More about Removing Human Bottlenecks in Bird Classification Using Camera Trap Images and Deep Learning.

The progenitor galaxies of stellar haloes as ‘failed’ Milky Ways (2023)
Journal Article
Bose, S., & Deason, A. J. (2023). The progenitor galaxies of stellar haloes as ‘failed’ Milky Ways. Monthly Notices of the Royal Astronomical Society, 522(4), 5013-5021. https://doi.org/10.1093/mnras/stad1123

The stellar halo of the Milky Way records the history of its interactions with dwarf galaxies, whose subsequent destruction results in the formation of an extended stellar component. Recent works have suggested that galaxies with masses comparable to... Read More about The progenitor galaxies of stellar haloes as ‘failed’ Milky Ways.

Estimating mesocarnivore abundance on commercial farmland using distance sampling with camera traps (2023)
Journal Article
McKaughan, J., Stephens, P., & Hill, R. (2023). Estimating mesocarnivore abundance on commercial farmland using distance sampling with camera traps. Ecological Solutions and Evidence, 4(2), Article e12229. https://doi.org/10.1002/2688-8319.12229

1. Mesocarnivores are of particular interest in wildlife management. Their adaptability makes them a focus of public attention globally, as negative interactions with people occur regularly, but their importance to wider ecosystem function is increas... Read More about Estimating mesocarnivore abundance on commercial farmland using distance sampling with camera traps.

Factors affecting bait uptake by the grey squirrel (Sciurus carolinensis) and the future delivery of oral contraceptives (2023)
Journal Article
Beatham, S., Coats, J., Stephens, P., & Massei, G. (online). Factors affecting bait uptake by the grey squirrel (Sciurus carolinensis) and the future delivery of oral contraceptives. Wildlife Research, 51, https://doi.org/10.1071/wr22159

Context: Invasive species negatively affect natural communities and human activities. The grey squirrel is an invasive species in the UK, causing damage to forestry and the decline of the native red squirrel. Oral contraceptives have the potential to... Read More about Factors affecting bait uptake by the grey squirrel (Sciurus carolinensis) and the future delivery of oral contraceptives.

Conglomerate Crystallization in the Cambridge Structural Database (2020–2021) (2023)
Journal Article
Walsh, M. P., Barclay, J. A., Begg, C. S., Xuan, J., & Kitching, M. O. (2023). Conglomerate Crystallization in the Cambridge Structural Database (2020–2021). Crystal Growth and Design, 23(4), 2837-2837. https://doi.org/10.1021/acs.cgd.3c00019

Conglomerate crystals are materials capable of undergoing spontaneous resolution and were responsible for the discovery of molecular chirality. Their relevance to modern chemical and crystallographic sciences has been hindered by the difficulty in id... Read More about Conglomerate Crystallization in the Cambridge Structural Database (2020–2021).