A simple one-pot oxidation protocol for the synthesis of dehydrohedione from Hedione
(2022)
Journal Article
Sharley, J. S., Gambacorta, G., Collado Pérez, A. M., Ferri, E. E., Miranda, A. F., Fernández, I. F., …Baxendale, I. R. (2022). A simple one-pot oxidation protocol for the synthesis of dehydrohedione from Hedione. Tetrahedron, 126, https://doi.org/10.1016/j.tet.2022.133068
A new method for the oxidation of Hedione 1 to dehydrohedione 2, a high value intermediate in the flavour and fragrance industry, has developed based upon one pot α-chlorination-elimination sequence which can be readily scaled. The spontaneous elimin... Read More about A simple one-pot oxidation protocol for the synthesis of dehydrohedione from Hedione.