Sniff and tell: the feasibility of using bio-detection dogs as a mobile diagnostic intervention for asymptomatic malaria in sub-Saharan Africa

Kasstan, B; Hampshire, K; Guest, C; Logan, JG; Pinder, M; Williams, K; D'Alessandro, U; Lindsay, SW

doi:10.1017/s0021932018000408

Impact of vector control interventions on malaria transmission intensity, outdoor vector biting rates and Anopheles mosquito species composition in Tororo, Uganda (2019)
Journal Article
Musiime, A. K., Smith, D. L., Kilama, M., Rek, J., Arinaitwe, E., Nankabirwa, J. I., Kamya, M. R., Conrad, M. D., Dorsey, G., Akol, A. M., Staedke, S. G., Lindsay, S. W., & Egonyu, J. P. (2019). Impact of vector control interventions on malaria transmission intensity, outdoor vector biting rates and Anopheles mosquito species composition in Tororo, Uganda. Malaria Journal, 18(1), Article 445. https://doi.org/10.1186/s12936-019-3076-4

Background Long-lasting insecticidal nets (LLINs) and indoor residual spraying of insecticide (IRS) are widely recommended for the prevention of malaria in endemic regions. Data from human landing catches provide information on the impact of vector c... Read More about Impact of vector control interventions on malaria transmission intensity, outdoor vector biting rates and Anopheles mosquito species composition in Tororo, Uganda.

Assessing the impact of the addition of pyriproxyfen on the durability of permethrin-treated bed nets in Burkina Faso: a compound-randomized controlled trial (2019)
Journal Article
Toé, K. H., Mechan, F., Tangena, J.-A. A., Morris, M., Solino, J., Tchicaya, E. F., Traoré, A., Ismail, H., Maas, J., Lissenden, N., Pinder, M., Lindsay, S. W., Tiono, A. B., Ranson, H., & Sagnon, N. (2019). Assessing the impact of the addition of pyriproxyfen on the durability of permethrin-treated bed nets in Burkina Faso: a compound-randomized controlled trial. Malaria Journal, 18, Article 383. https://doi.org/10.1186/s12936-019-3018-1

Background Long-lasting insecticidal nets (LLINs) treated with pyrethroids are the foundation of malaria control in sub-Saharan Africa. Rising pyrethroid resistance in vectors, however, has driven the development of alternative net formulations. Here... Read More about Assessing the impact of the addition of pyriproxyfen on the durability of permethrin-treated bed nets in Burkina Faso: a compound-randomized controlled trial.

Research agenda for preventing mosquito-transmitted diseases through improving the built environment in sub-Saharan Africa (2019)
Journal Article
Shenton, F. C., Addissie, A., Alabaster, G., Baziwe, D., Carrasco Tenezaca, M., Chinula, D., Jatta, E., Jawara, M., Jones, R., Knudsen, J., Krystosik, A. R., McCann, R., Murima, N., Mutuku, F., Nguela, R. L., Nieto Sanchez, C., Nix, E., Okumu, F., Ruel-Bergeron, S., Spitzen, J., …Lindsay, S. W. (2022). Research agenda for preventing mosquito-transmitted diseases through improving the built environment in sub-Saharan Africa. Cities and Health, 6(1), 72-80. https://doi.org/10.1080/23748834.2019.1684771

Mosquito-transmitted diseases are a major threat to health in sub-Saharan Africa, but could be reduced through modifications to the built environment. Here we report findings from a major workshop held to identify the research gaps in this area, name... Read More about Research agenda for preventing mosquito-transmitted diseases through improving the built environment in sub-Saharan Africa.

Knowledge gaps in the construction of rural healthy homes: A research agenda for improved low-cost housing in hot-humid Africa (2019)
Journal Article
von Seidlein, L., Wood, H., Brittain, O. S., Tusting, L., Bednarz, A., Mshamu, S., Kahabuka, C., Deen, J., Bell, D., Lindsay, S. W., & Knudsen, J. (2019). Knowledge gaps in the construction of rural healthy homes: A research agenda for improved low-cost housing in hot-humid Africa. PLoS Medicine, 16(10), Article e1002909. https://doi.org/10.1371/journal.pmed.1002909

Testing a pyriproxyfen auto-dissemination station attractive to gravid Anopheles gambiae sensu stricto for the development of a novel attract-release -and-kill strategy for malaria vector control (2019)
Journal Article
Mbare, O., Lindsay, S. W., & Fillinger, U. (2019). Testing a pyriproxyfen auto-dissemination station attractive to gravid Anopheles gambiae sensu stricto for the development of a novel attract-release -and-kill strategy for malaria vector control. BMC Infectious Diseases, 19(1), Article 800. https://doi.org/10.1186/s12879-019-4438-9

Background Larviciding is an effective supplementary tool for malaria vector control, but the identification and accessibility of aquatic habitats impedes application. Dissemination of the insect growth regulator, pyriproxyfen (PPF), by gravid Anophe... Read More about Testing a pyriproxyfen auto-dissemination station attractive to gravid Anopheles gambiae sensu stricto for the development of a novel attract-release -and-kill strategy for malaria vector control.

Pareto rules for malaria super-spreaders and super-spreading (2019)
Journal Article
Cooper, L., Kang, S. Y., Bisanzio, D., Maxwell, K., Rodriguez-Barraquer, I., Greenhouse, B., Drakeley, C., Arinaitwe, E., G. Staedke, S., Gething, P. W., Eckhoff, P., Reiner, R. C., Hay, S. I., Dorsey, G., Kamya, M. R., Lindsay, S. W., Grenfell, B. T., & Smith, D. L. (2019). Pareto rules for malaria super-spreaders and super-spreading. Nature Communications, 10(1), Article 3939. https://doi.org/10.1038/s41467-019-11861-y

Heterogeneity in transmission is a challenge for infectious disease dynamics and control. An 80-20 “Pareto” rule has been proposed to describe this heterogeneity whereby 80% of transmission is accounted for by 20% of individuals, herein called super-... Read More about Pareto rules for malaria super-spreaders and super-spreading.

Increased Threat of Urban Malaria from Anopheles stephensi Mosquitoes, Africa (2019)
Journal Article
Takken, W., & Lindsay, S. (2019). Increased Threat of Urban Malaria from Anopheles stephensi Mosquitoes, Africa. Emerging Infectious Diseases, 25(7), 1431-1432. https://doi.org/10.3201/eid2507.190301

Malaria continues to be a major health threat in Africa, mainly in rural areas. Recently, the urban malaria vector Anopheles stephensi invaded Djibouti and Ethiopia, potentially spreading to other areas of Africa. Urgent action is needed to prevent u... Read More about Increased Threat of Urban Malaria from Anopheles stephensi Mosquitoes, Africa.

Reduced mosquito survival in metal-roof houses may contribute to a decline in malaria transmission in sub-Saharan Africa (2019)
Journal Article
Lindsay, S. W., Jawara, M., Mwesigwa, J., Achan, J., Bayoh, N., Bradley, J., Kandeh, B., Kirby, M. J., Knudsen, J., Macdonald, M., Pinder, M., Tusting, L. S., Weiss, D. J., Wilson, A. L., & D’Alessandro, U. (2019). Reduced mosquito survival in metal-roof houses may contribute to a decline in malaria transmission in sub-Saharan Africa. Scientific Reports, 9(1), Article 7770. https://doi.org/10.1038/s41598-019-43816-0

In The Gambia, metal-roof houses were hotter during the day than thatched-roof houses. After 24 h, the mortality of Anopheles gambiae, the principal African malaria vector, was 38% higher in metal-roof houses than thatched ones. During the day, mosqu... Read More about Reduced mosquito survival in metal-roof houses may contribute to a decline in malaria transmission in sub-Saharan Africa.

Trained dogs identify people with malaria parasites by their odour (2019)
Journal Article
Guest, C., Pinder, M., Doggett, M., Squires, C., Affara, M., Kandeh, B., Dewhirst, S., Morant, S. V., D'Alessandro, U., Logan, J. G., & Lindsay, S. W. (2019). Trained dogs identify people with malaria parasites by their odour. The Lancet Infectious Diseases, 19(6), 578-580. https://doi.org/10.1016/s1473-3099%2819%2930220-8

Mapping changes in housing in sub-Saharan Africa from 2000 to 2015 (2019)
Journal Article
Tusting, L. S., Bisanzio, D., Alabaster, G., Cameron, E., Cibulskis, R., Davies, M., …Bhatt, S. (2019). Mapping changes in housing in sub-Saharan Africa from 2000 to 2015. Nature, 568, 391-394. https://doi.org/10.1038/s41586-019-1050-5

Access to adequate housing is a fundamental human right, essential to human security, nutrition and health, and a core objective of the United Nations Sustainable Development Goals1,2. Globally, the housing need is most acute in Africa, where the pop... Read More about Mapping changes in housing in sub-Saharan Africa from 2000 to 2015.

Sniff and tell: the feasibility of using bio-detection dogs as a mobile diagnostic intervention for asymptomatic malaria in sub-Saharan Africa (2019)
Journal Article
Kasstan, B., Hampshire, K., Guest, C., Logan, J., Pinder, M., Williams, K., …Lindsay, S. (2019). Sniff and tell: the feasibility of using bio-detection dogs as a mobile diagnostic intervention for asymptomatic malaria in sub-Saharan Africa. Journal of Biosocial Science, 51(3), 436-436-443. https://doi.org/10.1017/s0021932018000408

Bio-Detection Dogs (BDDs) are used in some high-income countries as a diagnostic intervention, yet little is known about their potential in low/middle-income countries with limited diagnostic resources. This exploratory study investigated the opportu... Read More about Sniff and tell: the feasibility of using bio-detection dogs as a mobile diagnostic intervention for asymptomatic malaria in sub-Saharan Africa.

All Outputs (11)