All Outputs (2)

Rafts and sphingolipid biosynthesis in the kinetoplastid parasitic protozoa (2004)
Journal Article
Denny, P., & Smith, D. (2004). Rafts and sphingolipid biosynthesis in the kinetoplastid parasitic protozoa. Molecular Microbiology, 53(3), 725-733. https://doi.org/10.1111/j.1365-2958.2004.04208.x

Although the concept of eukaryotic lipid rafts arouses controversy, recent biophysical studies strongly indicate that inducible, stable and relatively large rafts are a feature of activated mammalian cells. These studies allow us to consider the func... Read More about Rafts and sphingolipid biosynthesis in the kinetoplastid parasitic protozoa.

Sphingolipid-free Leishmania are defective in membrane trafficking, differentiation and infectivity (2004)
Journal Article
Denny, P., Goulding, D., Ferguson, M., & Smith, D. (2004). Sphingolipid-free Leishmania are defective in membrane trafficking, differentiation and infectivity. Molecular Microbiology, 52(2), 313-327. https://doi.org/10.1111/j.1365-2958.2003.03975.x

Sphingolipids are structural components of the eukaryotic plasma membrane that are involved, together with cholesterol, in the formation of lipid microdomains (rafts). Additionally, sphingolipid metabolites have been shown to modulate a wide variety... Read More about Sphingolipid-free Leishmania are defective in membrane trafficking, differentiation and infectivity.