All Outputs (3)

Insights into the antibacterial mechanism of action of chelating agents by selective deprivation of iron, manganese and zinc (2021)
Journal Article
Paterson, J. R., Beecroft, M. S., Mulla, R. S., Osman, D., Reeder, N. L., Caserta, J. A., …Sharples, G. J. (2022). Insights into the antibacterial mechanism of action of chelating agents by selective deprivation of iron, manganese and zinc. Applied and Environmental Microbiology, https://doi.org/10.1128/aem.01641-21

Bacterial growth and proliferation can be restricted by limiting the availability of metal ions in their environment. Humans sequester iron, manganese and zinc to help prevent infection by pathogens, a system termed nutritional immunity. Commercially... Read More about Insights into the antibacterial mechanism of action of chelating agents by selective deprivation of iron, manganese and zinc.

Bioinspired and eco-friendly high efficacy cinnamaldehyde antibacterial surfaces (2021)
Journal Article
Cox, H. J., Li, J., Saini, P., Paterson, J. R., Sharples, G. J., & Badyal, J. P. S. (2021). Bioinspired and eco-friendly high efficacy cinnamaldehyde antibacterial surfaces. Journal of Materials Chemistry B: Materials for biology and medicine, 9(12), 2918-2930. https://doi.org/10.1039/d0tb02379e

Antimicrobial essential oils are incorporated into mussel-inspired and natural plant polyphenol coatings as part of a single-step fabrication process. Polydopamine–cinnamaldehyde, polyethyleneimine–cinnamaldehyde, and tannic acid–cinnamaldehyde coati... Read More about Bioinspired and eco-friendly high efficacy cinnamaldehyde antibacterial surfaces.

A bacteriophage mimic of the bacterial nucleoid-associated protein Fis (2020)
Journal Article
Sharples, G. J., Heddle, J. G., Kozak, M., Taube, M., Hughes, T. R., Pålsson, L.-O., …Chakraborti, S. (2020). A bacteriophage mimic of the bacterial nucleoid-associated protein Fis. Biochemical Journal, 477(7), 1345-1362. https://doi.org/10.1042/bcj20200146

We report the identification and characterization of a bacteriophage λ-encoded protein, NinH. Sequence homology suggests similarity between NinH and Fis, a bacterial nucleoid-associated protein involved in numerous DNA topology manipulations, includi... Read More about A bacteriophage mimic of the bacterial nucleoid-associated protein Fis.