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Improving ART programme retention and viral suppression are key to maximising impact of treatment as prevention – a modelling study (2017)
Journal Article
McCreesh, N., Andrianakis, I., Nsubuga, R., Strong, M., Vernon, I., McKinley, T., …White, R. (2017). Improving ART programme retention and viral suppression are key to maximising impact of treatment as prevention – a modelling study. BMC Infectious Diseases, 17(1), Article 557. https://doi.org/10.1186/s12879-017-2664-6

Background UNAIDS calls for fewer than 500,000 new HIV infections/year by 2020, with treatment-as-prevention being a key part of their strategy for achieving the target. A better understanding of the contribution to transmission of people at differen... Read More about Improving ART programme retention and viral suppression are key to maximising impact of treatment as prevention – a modelling study.

Efficient History Matching of a High Dimensional Individual-Based HIV Transmission Model (2017)
Journal Article
Andrianakis, I., McCreesh, N., Vernon, I., McKinley, T., Oakley, J., Nsubuga, R., …White, R. (2017). Efficient History Matching of a High Dimensional Individual-Based HIV Transmission Model. SIAM/ASA Journal on Uncertainty Quantification, 5(1), 694-719. https://doi.org/10.1137/16m1093008

History matching is a model (pre-)calibration method that has been applied to computer models from a wide range of scientific disciplines. In this work we apply history matching to an individual-based epidemiological model of HIV that has 96 input an... Read More about Efficient History Matching of a High Dimensional Individual-Based HIV Transmission Model.

Universal test, treat, and keep: improving ART retention is key in cost-effective HIV control in Uganda (2017)
Journal Article
McCreesh, N., Andrianakis, I., Nsubuga, R., Strong, M., Vernon, I., McKinley, T., …White, R. (2017). Universal test, treat, and keep: improving ART retention is key in cost-effective HIV control in Uganda. BMC Infectious Diseases, 17, Article 322. https://doi.org/10.1186/s12879-017-2420-y

Background: With ambitious new UNAIDS targets to end AIDS by 2030, and new WHO treatment guidelines, there is increased interest in the best way to scale-up ART coverage. We investigate the cost-effectiveness of various ART scale-up options in Uganda... Read More about Universal test, treat, and keep: improving ART retention is key in cost-effective HIV control in Uganda.