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All Outputs (72)

Explaining variation in cancer survival between 11 jurisdictions in the International Cancer Benchmarking Partnership: a primary care vignette survey (2015)
Journal Article
Rose, P., Rubin, G., Perera-Salazar, R., Almberg, S., Barisic, A., Dawes, M., …Group, T. I. M. 3. W. (2015). Explaining variation in cancer survival between 11 jurisdictions in the International Cancer Benchmarking Partnership: a primary care vignette survey. BMJ Open, 5(5), Article e007212. https://doi.org/10.1136/bmjopen-2014-007212

Objectives The International Cancer Benchmarking Partnership (ICBP) is a collaboration between 6 countries and 12 jurisdictions with similar primary care-led health services. This study investigates primary care physician (PCP) behaviour and systems... Read More about Explaining variation in cancer survival between 11 jurisdictions in the International Cancer Benchmarking Partnership: a primary care vignette survey.

Age and gender variations in cancer diagnostic intervals in 15 cancers: analysis of data from the UK Clinical Practice Research Datalink (2015)
Journal Article
Din, N., Ukoumunne, O., Rubin, G., Hamilton, W., Carter, B., Stapley, S., & Neal, R. (2015). Age and gender variations in cancer diagnostic intervals in 15 cancers: analysis of data from the UK Clinical Practice Research Datalink. PLoS ONE, 10(5), Article e0127717. https://doi.org/10.1371/journal.pone.0127717

Background Time from symptomatic presentation to cancer diagnosis (diagnostic interval) is an important, and modifiable, part of the patient’s cancer pathway, and can be affected by various factors such as age, gender and type of presenting symptoms.... Read More about Age and gender variations in cancer diagnostic intervals in 15 cancers: analysis of data from the UK Clinical Practice Research Datalink.

The relative length of the patient and the primary care interval in patients with 28 common and rarer cancers (2015)
Journal Article
Lyratzopoulos, G., Saunders, C., Abel, G., McPhail, S., Neal, R., Wardle, J., & Rubin, G. (2015). The relative length of the patient and the primary care interval in patients with 28 common and rarer cancers. British Journal of Cancer, 112(s1), S35-S40. https://doi.org/10.1038/bjc.2015.40

Background: Appreciating variation in the length of pre- or post-presentation diagnostic intervals can help prioritise early diagnosis interventions with either a community or a primary care focus. Methods: We analysed data from the first English Nat... Read More about The relative length of the patient and the primary care interval in patients with 28 common and rarer cancers.

Symptoms and other factors associated with time to diagnosis and stage of lung cancer: a prospective cohort study (2015)
Journal Article
Walter, F., Rubin, G., Bankhead, C., Morris, H., Hall, N., Mills, K., …Emery, J. (2015). Symptoms and other factors associated with time to diagnosis and stage of lung cancer: a prospective cohort study. British Journal of Cancer, 112, S6-S13. https://doi.org/10.1038/bjc.2015.30

Background: This prospective cohort study aimed to identify symptom and patient factors that influence time to lung cancer diagnosis and stage at diagnosis. Methods: Data relating to symptoms were collected from patients upon referral with symptoms s... Read More about Symptoms and other factors associated with time to diagnosis and stage of lung cancer: a prospective cohort study.

The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports (2015)
Journal Article
Mitchell, E., Rubin, G., Merriman, L., & Macleod, U. (2015). The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports. British Journal of Cancer, 112, S50-S56. https://doi.org/10.1038/bjc.2015.42

Background: Patients diagnosed with cancer in the context of an emergency presentation (EP) have poorer outcomes. It is often assumed that such patients present to the emergency department without consulting their general practitioner (GP). Little wo... Read More about The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports.

Assessing the impact of an English national initiative for early cancer diagnosis in primary care (2015)
Journal Article
Rubin, G., Gildea, C., Wild, C., Shelton, J., & Ablett-Spence, I. (2015). Assessing the impact of an English national initiative for early cancer diagnosis in primary care. British Journal of Cancer, 112, S57-S64. https://doi.org/10.1038/bjc.2015.43

Background: The Cancer Networks Supporting Primary Care programme was a National Health Service (NHS) initiative in England between 2011 and 2013 that aimed to better understand and improve referral practices for suspected cancer. Methods: A mixed me... Read More about Assessing the impact of an English national initiative for early cancer diagnosis in primary care.

Impact of investigations in general practice on timeliness of referral for patients subsequently diagnosed with cancer: analysis of national primary care audit data (2015)
Journal Article
Rubin, G., Saunders, C., Abel, G., McPhail, S., Lyratzopoulos, G., & Neal, R. (2015). Impact of investigations in general practice on timeliness of referral for patients subsequently diagnosed with cancer: analysis of national primary care audit data. British Journal of Cancer, 112(4), 676-687. https://doi.org/10.1038/bjc.2014.634

Background: For patients with symptoms of possible cancer who do not fulfil the criteria for urgent referral, initial investigation in primary care has been advocated in the United Kingdom and supported by additional resources. The consequence of thi... Read More about Impact of investigations in general practice on timeliness of referral for patients subsequently diagnosed with cancer: analysis of national primary care audit data.

Patient delay in cancer diagnosis: what do we really mean and can we be more specific? (2014)
Journal Article
Dobson, C. M., Russell, A. J., & Rubin, G. P. (2014). Patient delay in cancer diagnosis: what do we really mean and can we be more specific?. BMC Health Services Research, 14(1), Article 387. https://doi.org/10.1186/1472-6963-14-387

Background: Early diagnosis is a key focus of cancer control because of its association with survival. Delays in diagnosis can occur throughout the diagnostic pathway, within any one of its three component intervals: the patient interval, the primary... Read More about Patient delay in cancer diagnosis: what do we really mean and can we be more specific?.

Factors associated with timeliness of post-primary care referral, diagnosis and treatment for lung cancer: population-based, data-linkage study (2014)
Journal Article
Forrest, L., Adams, J., White, M., & Rubin, G. (2014). Factors associated with timeliness of post-primary care referral, diagnosis and treatment for lung cancer: population-based, data-linkage study. British Journal of Cancer, 111(9), 1843-1851. https://doi.org/10.1038/bjc.2014.472

BACKGROUND: The NHS Cancer Plan for England set waiting time targets for cancer referral (14 days from GP referral to first hospital appointment) and treatment (31 days from diagnosis, 62 days from urgent GP referral). Interim diagnostic intervals ca... Read More about Factors associated with timeliness of post-primary care referral, diagnosis and treatment for lung cancer: population-based, data-linkage study.

Variation in promptness of presentation among 10,297 patients subsequently diagnosed with one of 18 cancers: Evidence from a National Audit of Cancer Diagnosis in Primary Care (2014)
Journal Article
Keeble, S., Abel, G., Saunders, C., McPhail, S., Walter, F., Neal, R., …Lyratzopoulos, G. (2014). Variation in promptness of presentation among 10,297 patients subsequently diagnosed with one of 18 cancers: Evidence from a National Audit of Cancer Diagnosis in Primary Care. International Journal of Cancer, 135(5), 1220-1228. https://doi.org/10.1002/ijc.28763

Cancer awareness public campaigns aim to shorten the interval between symptom onset and presentation to a doctor (the ‘patient interval’). Appreciating variation in promptness of presentation can help to better target awareness campaigns. We explored... Read More about Variation in promptness of presentation among 10,297 patients subsequently diagnosed with one of 18 cancers: Evidence from a National Audit of Cancer Diagnosis in Primary Care.

How might healthcare systems influence speed of cancer diagnosis: a narrative review (2014)
Journal Article
Brown, S., Castelli, M., Hunter, D., Erskine, J., Vedsted, P., Foot, C., & Rubin, G. (2014). How might healthcare systems influence speed of cancer diagnosis: a narrative review. Social Science & Medicine, 116, 56-63. https://doi.org/10.1016/j.socscimed.2014.06.030

Striking differences exist in outcomes for cancer between developed countries with comparable healthcare systems. We compare the healthcare systems of 3 countries (Denmark, Norway, Sweden), 3 UK jurisdictions (England, Wales and Northern Ireland), 3... Read More about How might healthcare systems influence speed of cancer diagnosis: a narrative review.

Development of a survey instrument to investigate the primary care factors related to differences in cancer diagnosis between international jurisdictions (2014)
Journal Article
Rose, P. W., Hamilton, W., Aldersey, K., Barisic, A., Dawes, M., Foot, C., …Group, T. I. M. 3. W. (2014). Development of a survey instrument to investigate the primary care factors related to differences in cancer diagnosis between international jurisdictions. BMC Family Practice, 15, Article 122. https://doi.org/10.1186/1471-2296-15-122

Background: Survival rates following a diagnosis of cancer vary between countries. The International Cancer Benchmarking Partnership (ICBP), a collaboration between six countries with primary care led health services, was set up in 2009 to investigat... Read More about Development of a survey instrument to investigate the primary care factors related to differences in cancer diagnosis between international jurisdictions.

The role of patient, tumour and system factors in socioeconomic inequalities in lung cancer treatment: population-based study (2014)
Journal Article
Forrest, L., White, M., Rubin, G., & Adams, J. (2014). The role of patient, tumour and system factors in socioeconomic inequalities in lung cancer treatment: population-based study. British Journal of Cancer, 111(3), 608-618. https://doi.org/10.1038/bjc.2014.310

BACKGROUND: Reducing socioeconomic inequalities in lung cancer treatment may reduce survival inequalities. However, the reasons for treatment variation are unclear. methods: Northern and Yorkshire cancer registry, Hospital Episode Statistics and lung... Read More about The role of patient, tumour and system factors in socioeconomic inequalities in lung cancer treatment: population-based study.

Socio-economic inequalities in patient, primary care, referral, diagnostic, and treatment intervals on the lung cancer care pathway: protocol for a systematic review and meta-analysis (2014)
Journal Article
Forrest, L., Sowden, S., Rubin, G., White, M., & Adams, J. (2014). Socio-economic inequalities in patient, primary care, referral, diagnostic, and treatment intervals on the lung cancer care pathway: protocol for a systematic review and meta-analysis. Systematic Reviews, 3, Article 30. https://doi.org/10.1186/2046-4053-3-30

Background: Early diagnosis and treatment of cancer is thought to be important for improving survival. Longer time between the onset of cancer symptoms and receipt of treatment may help explain the poorer survival of UK cancer patients compared to th... Read More about Socio-economic inequalities in patient, primary care, referral, diagnostic, and treatment intervals on the lung cancer care pathway: protocol for a systematic review and meta-analysis.

Comparison of cancer diagnostic intervals before and after implementation of NICE guidelines: analysis of data from the UK General Practice Research Database (2014)
Journal Article
Neal, R., Din, N., Hamilton, W., Ukoumunne, O., Carter, B., Stapley, S., & Rubin, G. (2014). Comparison of cancer diagnostic intervals before and after implementation of NICE guidelines: analysis of data from the UK General Practice Research Database. British Journal of Cancer, 110(3), 584-592. https://doi.org/10.1038/bjc.2013.791

Background: The primary aim was to use routine data to compare cancer diagnostic intervals before and after implementation of the 2005 NICE Referral Guidelines for Suspected Cancer. The secondary aim was to compare change in diagnostic intervals acro... Read More about Comparison of cancer diagnostic intervals before and after implementation of NICE guidelines: analysis of data from the UK General Practice Research Database.

Attitudes and beliefs of non-participants in a population-based screening programme for colorectal cancer (2013)
Journal Article
Hall, N., Rubin, G., Dobson, C., Weller, D., Wardle, J., Ritchie, M., & Rees, C. (2015). Attitudes and beliefs of non-participants in a population-based screening programme for colorectal cancer. Health Expectations, 18(5), 1645-1657. https://doi.org/10.1111/hex.12157

Background Uptake of colorectal cancer screening programmes needs to be improved or at least maintained in order to achieve projected reductions in mortality and morbidity. Understanding the origins of non-participation in screening is therefore impo... Read More about Attitudes and beliefs of non-participants in a population-based screening programme for colorectal cancer.

Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice – an evidence-based international guide (2013)
Journal Article
Hungin, A., Mulligan, C., Pot, B., Whorwell, P., Agréus, L., Fracasso, P., …de Wit, N. (2013). Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice – an evidence-based international guide. Alimentary Pharmacology and Therapeutics, 38(8), 864-886. https://doi.org/10.1111/apt.12460

Background Evidence suggests that the gut microbiota play an important role in gastrointestinal problems. Aim To give clinicians a practical reference guide on the role of specified probiotics in managing particular lower gastrointestinal symptoms/pr... Read More about Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice – an evidence-based international guide.

Intentional and inadvertent non-adherence in adult coeliac disease: a cross-sectional survey (2013)
Journal Article
Hall, N., Rubin, G., & Charnock, A. (2013). Intentional and inadvertent non-adherence in adult coeliac disease: a cross-sectional survey. Appetite, 68(1), 56-62. https://doi.org/10.1016/j.appet.2013.04.016

Adherence to a gluten-free diet is the mainstay of treatment for coeliac disease. Non-adherence is common as the diet is restrictive and can be difficult to follow. This study aimed to determine the rates of intentional and inadvertent non-adherence... Read More about Intentional and inadvertent non-adherence in adult coeliac disease: a cross-sectional survey.