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All Outputs (19)

Addressing the stiffness–toughness conflict in hybrid double-network hydrogels through a design of experiments approach † (2025)
Journal Article
Kopnar, V., Carlyle, L., Liu, E., Khaenyook, S., O'Connell, A., Shirshova, N., & Aufderhorst-Roberts, A. (2025). Addressing the stiffness–toughness conflict in hybrid double-network hydrogels through a design of experiments approach †. Soft Matter, 21, 3604-3612. https://doi.org/10.1039/d4sm01470g

An open challenge in soft matter science is the ability to create hydrogels that are soft but also have high fracture energy. A possible solution to this stiffness–toughness conflict has arisen through a class of material known as hybrid double-netwo... Read More about Addressing the stiffness–toughness conflict in hybrid double-network hydrogels through a design of experiments approach †.

A New Approach for On-Chip Production of Biological Microgels Using Photochemical Cross-Linking (2024)
Journal Article
Del Giudice, F., Curtis, D. J., & Aufderhorst-Roberts, A. (2024). A New Approach for On-Chip Production of Biological Microgels Using Photochemical Cross-Linking. Analytical Chemistry, 96(25), 10140-10144. https://doi.org/10.1021/acs.analchem.4c01574

Photochemical cross-linking is a key step for manufacturing microgels in numerous applications, including drug delivery, tissue engineering, material production, and wound healing. Existing photochemical cross-linking techniques in microfluidic devic... Read More about A New Approach for On-Chip Production of Biological Microgels Using Photochemical Cross-Linking.

Diversity of viscoelastic properties of an engineered muscle-inspired protein hydrogel (2023)
Journal Article
Aufderhorst-Roberts, A., Cussons, S., Brockwell, D. J., & Dougan, L. (2023). Diversity of viscoelastic properties of an engineered muscle-inspired protein hydrogel. Soft Matter, 19(17), 3167-3178. https://doi.org/10.1039/d2sm01225a

Folded protein hydrogels are prime candidates as tuneable biomaterials but it is unclear to what extent their mechanical properties have mesoscopic, as opposed to molecular origins. To address this, we probe hydrogels inspired by the muscle protein t... Read More about Diversity of viscoelastic properties of an engineered muscle-inspired protein hydrogel.

Scratching beyond the surface — minimal actin assemblies as tools to elucidate mechanical reinforcement and shape change (2022)
Journal Article
Aufderhorst-Roberts, A., & Staykova, M. (2022). Scratching beyond the surface — minimal actin assemblies as tools to elucidate mechanical reinforcement and shape change. Emerging Topics in Life Sciences, 6(6), 583-592. https://doi.org/10.1042/etls20220052

The interaction between the actin cytoskeleton and the plasma membrane in eukaryotic cells is integral to a large number of functions such as shape change, mechanical reinforcement and contraction. These phenomena are driven by the architectural regu... Read More about Scratching beyond the surface — minimal actin assemblies as tools to elucidate mechanical reinforcement and shape change.