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All Outputs (73)

Guidelines for the investigation of chronic diarrhoea in adults: British Society of Gastroenterology, 3rd edition (2018)
Journal Article
Arasaradnam, R. P., Brown, S., Forbes, A., Fox, M. R., Hungin, P., Kelman, L., Major, G., O’Connor, M., Sanders, D. S., Sinha, R., Smith, S. C., Thomas, P., & Walters, J. R. (2018). Guidelines for the investigation of chronic diarrhoea in adults: British Society of Gastroenterology, 3rd edition. Gut, 67(8), 1380-1399. https://doi.org/10.1136/gutjnl-2017-315909

Chronic diarrhoea is a common problem, hence clear guidance on investigations is required. This is an updated guideline from 2003 for the investigations of chronic diarrhoea commissioned by the Clinical Services and Standards Committee of the British... Read More about Guidelines for the investigation of chronic diarrhoea in adults: British Society of Gastroenterology, 3rd edition.

Reliable exclusion of prognostically significant coronary disease in left ventricular dysfunction by cardiac MRI (2016)
Journal Article
Thompson, A., Crilley, J., Wilson, D., Hungin, A., Fuat, A., & Murphy, J. (2017). Reliable exclusion of prognostically significant coronary disease in left ventricular dysfunction by cardiac MRI. Clinical Radiology, 72(2), 159-164. https://doi.org/10.1016/j.crad.2016.10.006

Aim To assess the ability of cardiac magnetic resonance (CMR) to exclude prognostically significant coronary artery disease (CAD) in patients with left ventricular systolic dysfunction (LVSD). Materials and methods A cohort of patients who underwent... Read More about Reliable exclusion of prognostically significant coronary disease in left ventricular dysfunction by cardiac MRI.

Transition from childhood to adulthood in coeliac disease: the Prague consensus report (2016)
Journal Article
Ludvigsson, J., Agreus, L., Ciacci, C., Crowe, S., Geller, M., Green, P., …Husby, S. (2016). Transition from childhood to adulthood in coeliac disease: the Prague consensus report. Gut, 65(8), 1242-1251. https://doi.org/10.1136/gutjnl-2016-311574

The process of transition from childhood to adulthood is characterised by physical, mental and psychosocial development. Data on the transition and transfer of care in adolescents/young adults with coeliac disease (CD) are scarce. In this paper, 17 p... Read More about Transition from childhood to adulthood in coeliac disease: the Prague consensus report.

Faecal biomarker patterns in patients with symptoms of irritable bowel syndrome (2016)
Journal Article
Emmanuel, A., Landis, D., Peucker, M., & Hungin, A. (2016). Faecal biomarker patterns in patients with symptoms of irritable bowel syndrome. Frontline Gastroenterology, 7(4), 275-282. https://doi.org/10.1136/flgastro-2015-100651

Objective: To determine rates of faecal biomarker results capable of suggesting potentially treatable causes of irritable bowel syndrome (IBS) symptomatology in a population of patients with symptoms of IBS who meet Rome III criteria for that conditi... Read More about Faecal biomarker patterns in patients with symptoms of irritable bowel syndrome.

The global prevalence of IBS in adults remains elusive due to the heterogeneity of studies: a Rome Foundation working team literature review (2016)
Journal Article
Sperber, A., Dumitrascu, D., Fukudo, S., Gerson, C., Ghoshal, U., Gwee, K., …Whitehead, W. (2017). The global prevalence of IBS in adults remains elusive due to the heterogeneity of studies: a Rome Foundation working team literature review. Gut, 66(6), 1075-1082. https://doi.org/10.1136/gutjnl-2015-311240

Objectives The global prevalence of IBS is difficult to ascertain, particularly in light of the heterogeneity of published epidemiological studies. The aim was to conduct a literature review, by experts from around the world, of community-based studi... Read More about The global prevalence of IBS in adults remains elusive due to the heterogeneity of studies: a Rome Foundation working team literature review.

Prevalence, symptom patterns and management of episodic diarrhoea in the community: a population-based survey in 11 countries (2016)
Journal Article
Hungin, A., Paxman, L., Koenig, K., Dalrymple, J., Wicks, N., & Walmsley, J. (2016). Prevalence, symptom patterns and management of episodic diarrhoea in the community: a population-based survey in 11 countries. Alimentary Pharmacology and Therapeutics, 43(5), 586-595. https://doi.org/10.1111/apt.13513

Background: The extent of episodic diarrhoea in the community is relatively unknown. Aim: To ascertain the prevalence, symptoms and management behaviours associated with self-reported diarrhoea across 11 countries. Methods: Community screening survey... Read More about Prevalence, symptom patterns and management of episodic diarrhoea in the community: a population-based survey in 11 countries.

Discrepancies between upper GI symptoms described by those who have them and their identification by conventional medical terminology: a survey of sufferers in four countries (2016)
Journal Article
Heading, R., Thomas, E., Sandy, P., Smith, G., Fass, R., & Hungin, P. (2016). Discrepancies between upper GI symptoms described by those who have them and their identification by conventional medical terminology: a survey of sufferers in four countries. European Journal of Gastroenterology & Hepatology, 28(4), 455-462. https://doi.org/10.1097/meg.0000000000000565

Objective: The objective of this study was to develop a self-administered questionnaire for upper gastrointestinal (GI) symptoms using lay vocabulary uninfluenced by established medical terminology or concepts and to conduct a survey of symptom occur... Read More about Discrepancies between upper GI symptoms described by those who have them and their identification by conventional medical terminology: a survey of sufferers in four countries.

Risk of ischaemic heart disease in patients with inflammatory bowel disease: cohort study using the General Practice Research Database (2015)
Journal Article
Close, H., Mason, J., Wilson, D., Hungin, A., Jones, R., & Rubin, G. (2015). Risk of ischaemic heart disease in patients with inflammatory bowel disease: cohort study using the General Practice Research Database. PLoS ONE, 10(10), Article e0139745. https://doi.org/10.1371/journal.pone.0139745

Objective Patients with inflammatory bowel disease (IBD) demonstrate an inflammatory response which bears some similarities to that seen in ischaemic heart disease (IHD). The nature of the association of IBD with IHD is uncertain. We aimed to define... Read More about Risk of ischaemic heart disease in patients with inflammatory bowel disease: cohort study using the General Practice Research Database.

Gastro-oesophageal reflux disease: Illness or illusion? (2015)
Journal Article
Hungin, A. (2015). Gastro-oesophageal reflux disease: Illness or illusion?. British Journal of General Practice, 65(637), 392-393. https://doi.org/10.3399/bjgp15x685993

Gastro-oesophageal reflux disease (GORD) is well entrenched in the clinician’s mind. But, is it a spurious or artificial concept and what do we actually know about it? There are just too many things that don’t add up. When communicating with patients... Read More about Gastro-oesophageal reflux disease: Illness or illusion?.

Irritable bowel syndrome: an integrated explanatory model for clinical practice (2015)
Journal Article
Hungin, A., Becher, A., Cayley, B., Heidelbaugh, J., Muris, J., Rubin, G., …De Wit, N. (2015). Irritable bowel syndrome: an integrated explanatory model for clinical practice. Neurogastroenterology and Motility, 27(6), 750-763. https://doi.org/10.1111/nmo.12524

Background Although irritable bowel syndrome (IBS) is a symptom-based diagnosis, clinicians' management of and communication about the disorder is often hampered by an unclear conceptual understanding of the nature of the problem. We aimed to elucida... Read More about Irritable bowel syndrome: an integrated explanatory model for clinical practice.

Barriers to accurate diagnosis and effective management of heart failure have not changed in the past 10 years: a qualitative study and national survey (2014)
Journal Article
Hancock, H., Close, H., Fuat, A., Murphy, J., Hungin, A., & Mason, J. (2014). Barriers to accurate diagnosis and effective management of heart failure have not changed in the past 10 years: a qualitative study and national survey. BMJ Open, 4(3), Article e003866. https://doi.org/10.1136/bmjopen-2013-003866

Objectives: To explore changes in healthcare professionals’ views about the diagnosis and management of heart failure since a study in 2003. Design: Focus groups and a national online cross-sectional survey. Setting and participants: Focus groups (n=... Read More about Barriers to accurate diagnosis and effective management of heart failure have not changed in the past 10 years: a qualitative study and national survey.

Developing a clinical research network: the Northern Region Endoscopy Group experience (2014)
Journal Article
Rajasekhar, P., Rees, C., Rutter, M., & Hungin, P. (2014). Developing a clinical research network: the Northern Region Endoscopy Group experience. Clinical medicine (London. Online), 14(2), 107-112. https://doi.org/10.7861/clinmedicine.14-2-107

Research is central to the National Health Service. Clinical trial recruitment has been aided by the National Institute for Health Research's Comprehensive Research Network but these networks do not support development of research. The Northern Regio... Read More about Developing a clinical research network: the Northern Region Endoscopy Group experience.

Renal Failure in Lithium-Treated Bipolar Disorder: A Retrospective Cohort Study (2014)
Journal Article
Close, H., Reilly, J., Mason, J., Mukesh, K., Wilson, D., Main, J., & Hungin, A. (2014). Renal Failure in Lithium-Treated Bipolar Disorder: A Retrospective Cohort Study. PLoS ONE, 9(3), Article e90169. https://doi.org/10.1371/journal.pone.0090169

Objective: Lithium users are offered routine renal monitoring but few studies have quantified the risk to renal health. The aim of this study was to assess the association between use of lithium carbonate and incidence of renal failure in patients wi... Read More about Renal Failure in Lithium-Treated Bipolar Disorder: A Retrospective Cohort Study.

Multidetector CT Improving Surgical Outcomes in Breast Cancer (MISO BC) (2014)
Presentation / Conference Contribution
Cox, J., Hancock, H., Spratt, J., Close, H., Lee, C., Mohammed, U., & Mason, J. Multidetector CT Improving Surgical Outcomes in Breast Cancer (MISO BC). Presented at British Society of Breast Radiology Annual Scientific Meeting 2014, Brighton, England

Introduction: This multicentre randomised controlled trial investigated whether a computed tomography (CT) scan of the axilla could more accurately assess whether the axillary lymph nodes were involved with malignancy in patients with newly diagnosed... Read More about Multidetector CT Improving Surgical Outcomes in Breast Cancer (MISO BC).

Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice – an evidence-based international guide (2013)
Journal Article
Hungin, A., Mulligan, C., Pot, B., Whorwell, P., Agréus, L., Fracasso, P., …de Wit, N. (2013). Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice – an evidence-based international guide. Alimentary Pharmacology and Therapeutics, 38(8), 864-886. https://doi.org/10.1111/apt.12460

Background Evidence suggests that the gut microbiota play an important role in gastrointestinal problems. Aim To give clinicians a practical reference guide on the role of specified probiotics in managing particular lower gastrointestinal symptoms/pr... Read More about Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice – an evidence-based international guide.

“It’s Somebody else’s responsibility” - perceptions of general practitioners, heart failure nurses, care home staff, and residents towards heart failure diagnosis and management for older people in long-term care: a qualitative interview study (2013)
Journal Article
Close, H., Hancock, H., Mason, J. M., Murphy, J. J., Fuat, A., de Belder, M., & Hungin, A. P. S. (2013). “It’s Somebody else’s responsibility” - perceptions of general practitioners, heart failure nurses, care home staff, and residents towards heart failure diagnosis and management for older people in long-term care: a qualitative interview study. BMC Geriatrics, 13, Article 69. https://doi.org/10.1186/1471-2318-13-69

Background: Older people in care-facilities may be less likely to access gold standard diagnosis and treatment for heart failure (HF) than non residents; little is understood about the factors that influence this variability. This study aimed to exam... Read More about “It’s Somebody else’s responsibility” - perceptions of general practitioners, heart failure nurses, care home staff, and residents towards heart failure diagnosis and management for older people in long-term care: a qualitative interview study.

Utility of Biomarkers in the Differential Diagnosis of Heart Failure in Older People: Findings from the Heart Failure In Care Homes (HFinCH) Diagnostic Accuracy Study (2013)
Journal Article
Mason, J., Hancock, H., Close, H., Murphy, J., Fuat, A., de Belder, M., …Hungin, P. (2013). Utility of Biomarkers in the Differential Diagnosis of Heart Failure in Older People: Findings from the Heart Failure In Care Homes (HFinCH) Diagnostic Accuracy Study. PLoS ONE, 8(1), Article e53560. https://doi.org/10.1371/journal.pone.0053560

Achieving high quality colonoscopy: Using graphical representation to measure performance and reset standards (2012)
Journal Article
Rajasekhar, P., Rutter, M., Bramble, M., Wilson, D., East, J., Greenaway, J., …Rees, C. (2012). Achieving high quality colonoscopy: Using graphical representation to measure performance and reset standards. Colorectal Disease, 14(11), 1538-1545. https://doi.org/10.1111/j.1463-1318.2012.03057.x

Aim:  Completeness and thoroughness of colonoscopy are measured by the caecal intubation rate (CIR) and the adenoma detection rate (ADR). National standards are ≥ 90% and ≥ 10% respectively. Variability in CIR, ADR have been demonstrated but comparis... Read More about Achieving high quality colonoscopy: Using graphical representation to measure performance and reset standards.

Feasibility of evidence-based diagnosis and management of heart failure in older people in care: a pilot randomised controlled trial (2012)
Journal Article
Hancock, H., Close, H., Mason, J., Murphy, J., Fuat, A., de Belder, M., …Hungin, A. P. S. (2012). Feasibility of evidence-based diagnosis and management of heart failure in older people in care: a pilot randomised controlled trial. BMC Geriatrics, 12, Article 70. https://doi.org/10.1186/1471-2318-12-70

Background: Many older people in long-term care do not receive evidence-based diagnosis or management for heart failure; it is not known whether this can be achieved for this population. We initiated an onsite heart failure service, compared with ‘us... Read More about Feasibility of evidence-based diagnosis and management of heart failure in older people in care: a pilot randomised controlled trial.