Bat teeth illuminate the diversification of mammalian tooth classes

Sadier, Alexa; Anthwal, Neal; Krause, Andrew L.; Dessalles, Renaud; Lake, Michael; Bentolila, Laurent A.; Haase, Robert; Nieves, Natalie A.; Santana, Sharlene E.; Sears, Karen E.

Abstract

Tooth classes are an innovation that has contributed to the evolutionary success of mammals. However, our understanding of the mechanisms by which tooth classes diversified remain limited. We use the evolutionary radiation of noctilionoid bats to show how the tooth developmental program evolved during the adaptation to new diet types. Combining morphological, developmental and mathematical modeling approaches, we demonstrate that tooth classes develop through independent developmental cascades that deviate from classical models. We show that the diversification of tooth number and size is driven by jaw growth rate modulation, explaining the rapid gain/loss of teeth in this clade. Finally, we mathematically model the successive appearance of tooth buds, supporting the hypothesis that growth acts as a key driver of the evolution of tooth number and size. Our work reveal how growth, by tinkering with reaction/diffusion processes, drives the diversification of tooth classes and other repeated structure during adaptive radiations.

Citation

Sadier, A., Anthwal, N., Krause, A. L., Dessalles, R., Lake, M., Bentolila, L. A., …Sears, K. E. (2023). Bat teeth illuminate the diversification of mammalian tooth classes. Nature Communications, 14(1), Article 4687. https://doi.org/10.1038/s41467-023-40158-4

• Journal Article Type: Article
• Acceptance Date: Jul 11, 2023
• Online Publication Date: Aug 22, 2023
• Publication Date: 2023
• Deposit Date: Oct 9, 2023
• Publicly Available Date: Oct 9, 2023
• Journal: Nature Communications
• Publisher: Nature Research
• Peer Reviewed: Peer Reviewed
• Volume: 14
• Issue: 1
• Article Number: 4687
• DOI: https://doi.org/10.1038/s41467-023-40158-4
• Public URL: https://durham-repository.worktribe.com/output/1787960