Current directions in co-crystal growth

Blagden, N.; Berry, D.J.; Parkin, A.; Javed, H.; Ibrahim, A.; Gavan, P.T.; De Matos, L.L.; Seaton, C.C.

Abstract

In this feature article we will focus on the issues relating to the crystal growth of co-crystals, with a particular emphasis on drug development. The initial focus of this perspective is on the relevant literature examples that may be able to inform our understanding with regards co-crystal crystallisation and the allied supramolecular concepts. The second part of this perspective contains selected examples from our own work, which add to the literature perspective. Topics include; nucleation templates, in situ synchrotron XRD studies, solid-state synthesis through mixing and screening strategies.

Citation

Blagden, N., Berry, D., Parkin, A., Javed, H., Ibrahim, A., Gavan, P., …Seaton, C. (2008). Current directions in co-crystal growth. New Journal of Chemistry, 32(10), 1659-1672. https://doi.org/10.1039/b803866j

• Journal Article Type: Article
• Publication Date: Oct 1, 2008
• Deposit Date: Mar 4, 2013
• Journal: New Journal of Chemistry
• Print ISSN: 1144-0546
• Electronic ISSN: 1369-9261
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 32
• Issue: 10
• Pages: 1659-1672
• DOI: https://doi.org/10.1039/b803866j
• Public URL: https://durham-repository.worktribe.com/output/1467561