Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis
(2022)
Journal Article
Datta, H. K., Kringen, M. K., Tuck, S. P., Salpingidou, G., Olstad, O. K., Gautvik, K. M., Cockell, S. J., Gautvik, V. T., Prediger, M., Wu, J. J., Birch, M. A., & Reppe, S. (2022). Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis. International Journal of Molecular Sciences, 23(6), Article 2957. https://doi.org/10.3390/ijms23062957
Mechanical loading exerts a profound influence on bone density and architecture, but the exact mechanism is unknown. Our study shows that expression of the neurological transcriptional factor zinc finger of the cerebellum 1 (ZIC1) is markedly increas... Read More about Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis.