Outputs (151)

The impact of climate on the abundance of Musca sorbens, the vector of trachoma (2016)
Journal Article
Ramesh, A., Bristow, J., Kovats, S., Lindsay, S., Haslam, D., Schmidt, E., & Gilbert, C. (2016). The impact of climate on the abundance of Musca sorbens, the vector of trachoma. Parasites and Vectors, 9(1), Article 48. https://doi.org/10.1186/s13071-016-1330-y

Background: To assess the extent to which climate may affect the abundance of Musca sorbens, a putative vector of trachoma. Data sources: Studies were identified by systematically searching online databases including CAB abstracts, Embase, Global Hea... Read More about The impact of climate on the abundance of Musca sorbens, the vector of trachoma.

Measuring Socioeconomic Inequalities in Relation to Malaria Risk: A Comparison of Metrics in Rural Uganda (2016)
Journal Article
Tusting, L., Rek, J., Arinaitwe, E., Staedke, S., Kamya, M., Bottomley, C., …Lindsay, S. (2016). Measuring Socioeconomic Inequalities in Relation to Malaria Risk: A Comparison of Metrics in Rural Uganda. American Journal of Tropical Medicine and Hygiene, 94(3), 650-658. https://doi.org/10.4269/ajtmh.15-0554

Socioeconomic position (SEP) is an important risk factor for malaria, but there is no consensus on how to measure SEP in malaria studies. We evaluated the relative strength of four indicators of SEP in predicting malaria risk in Nagongera, Uganda. A... Read More about Measuring Socioeconomic Inequalities in Relation to Malaria Risk: A Comparison of Metrics in Rural Uganda.

Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase (2016)
Journal Article
Aldred, K., Blower, T., Kerns, R., Berger, J., & Osheroff, N. (2016). Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase. Proceedings of the National Academy of Sciences, 113(7), E839-E846. https://doi.org/10.1073/pnas.1525055113

Mycobacterium tuberculosis is a significant source of global morbidity and mortality. Moxifloxacin and other fluoroquinolones are important therapeutic agents for the treatment of tuberculosis, particularly multidrug-resistant infections. To guide th... Read More about Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase.

Crystal structure and stability of gyrase–fluoroquinolone cleaved complexes from Mycobacterium tuberculosis (2016)
Journal Article
Blower, T., Williamson, B., Kerns, R., & Berger, J. (2016). Crystal structure and stability of gyrase–fluoroquinolone cleaved complexes from Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences, 113(7), 1706-1713. https://doi.org/10.1073/pnas.1525047113

Mycobacterium tuberculosis (Mtb) infects one-third of the world’s population and in 2013 accounted for 1.5 million deaths. Fluoroquinolone antibacterials, which target DNA gyrase, are critical agents used to halt the progression from multidrug-resist... Read More about Crystal structure and stability of gyrase–fluoroquinolone cleaved complexes from Mycobacterium tuberculosis.

Terrestrial biosphere changes over the last 120 kyr (2016)
Journal Article
Hoogaker, B., Smith, R., Singarayer, J., Marchant, R., Prentice, I., Allen, J., …Tzedakis, C. (2016). Terrestrial biosphere changes over the last 120 kyr. Climate of the Past, 12(1), 51-73. https://doi.org/10.5194/cp-12-51-2016

A new global synthesis and biomization of long (> 40 kyr) pollen-data records is presented and used with simulations from the HadCM3 and FAMOUS climate models and the BIOME4 vegetation model to analyse the dynamics of the global terrestrial biosphere... Read More about Terrestrial biosphere changes over the last 120 kyr.

Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68 (2016)
Journal Article
Feracci, M., Foot, J. N., Grellscheid, S. N., Danilenko, M., Stehle, R., Gonchar, O., …Dominguez, C. (2016). Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68. Nature Communications, 7, Article 10355. https://doi.org/10.1038/ncomms10355

Sam68 and T-STAR are members of the STAR family of proteins that directly link signal transduction with post-transcriptional gene regulation. Sam68 controls the alternative splicing of many oncogenic proteins. T-STAR is a tissue-specific paralogue th... Read More about Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.

The ecological and evolutionary stability of interspecific territoriality (2016)
Journal Article
Losin, N., Drury, J., Peiman, K., Storch, C., & Grether, G. (2016). The ecological and evolutionary stability of interspecific territoriality. Ecology Letters, 19(3), 260-267. https://doi.org/10.1111/ele.12561

Interspecific territoriality may play an important role in structuring ecological communities, but the causes of this widespread form of interference competition remain poorly understood. Here, we investigate the phenotypic, ecological and phylogenet... Read More about The ecological and evolutionary stability of interspecific territoriality.

Achieving and communicating globally relevant applied ecological research (2016)
Journal Article
Barlow, J., Cadotte, M., Newton, E., Pettorelli, N., Plane, A., Stephens, P., & Whittingham, M. (2016). Achieving and communicating globally relevant applied ecological research. Journal of Applied Ecology, 53(1), 1-4. https://doi.org/10.1111/1365-2664.12587

Beyond climate envelope projections: Roe deer survival and environmental change (2016)
Journal Article
Davis, M., Stephens, P., & Kjellander, P. (2016). Beyond climate envelope projections: Roe deer survival and environmental change. The Journal of Wildlife Management, 80(3), 452-464. https://doi.org/10.1002/jwmg.1029

Research on climate change impacts has focused on projecting changes in the geographic ranges of species, with less emphasis on the vital rates giving rise to species distributions. Managing ungulate populations under future climate change will requi... Read More about Beyond climate envelope projections: Roe deer survival and environmental change.

Cortical PAR polarity proteins promote robust cytokinesis during asymmetric cell division (2016)
Journal Article
Jordan, S. N., Davies, T., Zhuravlev, Y., Dumont, J., Shirasu-Hiza, M., & Canman, J. C. (2016). Cortical PAR polarity proteins promote robust cytokinesis during asymmetric cell division. Journal of Cell Biology, 212(1), 39-49. https://doi.org/10.1083/jcb.201510063

Cytokinesis, the physical division of one cell into two, is thought to be fundamentally similar in most animal cell divisions and driven by the constriction of a contractile ring positioned and controlled solely by the mitotic spindle. During asymmet... Read More about Cortical PAR polarity proteins promote robust cytokinesis during asymmetric cell division.