Outputs (2)

Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells (2010)
Journal Article
Howes, M., Kirkham, M., Riches, J., Cortese, K., Walser, P., Simpson, F., …Parton, R. (2010). Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells. Journal of Cell Biology, 190(4), 675-691. https://doi.org/10.1083/jcb.201002119

Although the importance of clathrin- and caveolin-independent endocytic pathways has recently emerged, key aspects of these routes remain unknown. Using quantitative ultrastructural approaches, we show that clathrin-independent carriers (CLICs) accou... Read More about Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells.

Recessive mutations in the putative calcium-activated chloride channel Anoctamin 5 cause proximal LGMD2L and distal MMD3 muscular dystrophies. (2010)
Journal Article
Bolduc, V., Marlow, G., Boycott, K., Saleki, K., Inoue, H., Kroon, J., …Brais, B. (2010). Recessive mutations in the putative calcium-activated chloride channel Anoctamin 5 cause proximal LGMD2L and distal MMD3 muscular dystrophies. American Journal of Human Genetics, 86(2), 213-221. https://doi.org/10.1016/j.ajhg.2009.12.013

The recently described human anion channel Anoctamin (ANO) protein family comprises at least ten members, many of which have been shown to correspond to calcium-activated chloride channels. To date, the only reported human mutations in this family of... Read More about Recessive mutations in the putative calcium-activated chloride channel Anoctamin 5 cause proximal LGMD2L and distal MMD3 muscular dystrophies..