Outputs (6)

Evaluation of the anti-nociceptive profile of essential oil from Melissa officinalis L. (lemon balm) in acute and chronic pain models (2023)
Journal Article
Chindo, B. A., Howes, M. R., Abuhamdah, S., Mallam, D., Micah, T., Awotula, R. I., …Chazot, P. L. (2024). Evaluation of the anti-nociceptive profile of essential oil from Melissa officinalis L. (lemon balm) in acute and chronic pain models. Journal of Ethnopharmacology, 321, Article 117500. https://doi.org/10.1016/j.jep.2023.117500

Ethnopharmacological relevance
Melissa officinalis L. (Lamiaceae) is a medicinal plant native to Mediterranean regions and found in other parts of the world. Extracts and essential oil from this widely cultivated culinary medicinal herb are used in... Read More about Evaluation of the anti-nociceptive profile of essential oil from Melissa officinalis L. (lemon balm) in acute and chronic pain models.

Attenuation of Vanadium-Induced Neurotoxicity in Rat Hippocampal Slices (In Vitro) and Mice (In Vivo) by ZA-II-05, a Novel NMDA-Receptor Antagonist (2023)
Journal Article
Digal Ladagu, A., Eniola Olopade, F., Chazot, P., Oyagbemi, A. A., Ohiomokhare, S., Racheal Folarin, O., …Olopade, J. O. (2023). Attenuation of Vanadium-Induced Neurotoxicity in Rat Hippocampal Slices (In Vitro) and Mice (In Vivo) by ZA-II-05, a Novel NMDA-Receptor Antagonist. International Journal of Molecular Sciences, 24(23), Article 16710. https://doi.org/10.3390/ijms242316710

Exposure to heavy metals, such as vanadium, poses an ongoing environmental and health threat, heightening the risk of neurodegenerative disorders. While several compounds have shown promise in mitigating vanadium toxicity, their efficacy is limited.... Read More about Attenuation of Vanadium-Induced Neurotoxicity in Rat Hippocampal Slices (In Vitro) and Mice (In Vivo) by ZA-II-05, a Novel NMDA-Receptor Antagonist.

Confidence of practitioners to support self-management of pain: A multidisciplinary survey (2023)
Journal Article
Penlington, C., Pornsukjantra, P., Chazot, P., Cole, F., & Denneny, D. (2024). Confidence of practitioners to support self-management of pain: A multidisciplinary survey. British Journal of Pain, 18(2), 148-154. https://doi.org/10.1177/20494637231212748

Background: Supported self-management is an important component of management for persistent pain according to current recommendations and guidelines. However, it is unclear whether staff from differing disciplines who may be in early contact with pe... Read More about Confidence of practitioners to support self-management of pain: A multidisciplinary survey.

Blood-Based Biomarkers in the Diagnosis of Chronic Traumatic Encephalopathy: Research to Date and Future Directions (2023)
Journal Article
Halicki, M. J., Hind, K., & Chazot, P. L. (2023). Blood-Based Biomarkers in the Diagnosis of Chronic Traumatic Encephalopathy: Research to Date and Future Directions. International Journal of Molecular Sciences, 24(16), Article 12556. https://doi.org/10.3390/ijms241612556

Chronic Traumatic Encephalopathy (CTE) is a neurodegenerative disease consistently associated with repetitive traumatic brain injuries (TBIs), which makes multiple professions, such as contact sports athletes and the military, especially susceptible... Read More about Blood-Based Biomarkers in the Diagnosis of Chronic Traumatic Encephalopathy: Research to Date and Future Directions.

Pain through the perspective of art and creativity: insights from the Unmasking Pain project (2023)
Journal Article
Johnson, M. I., Chazot, P., Cole, F., Cruickshank, R., Fuller, D., Keyse, C., Singh, B., Strickson, A. J., Tabasam, G., Tregidden, E., Thompson, K., & Woodall, J. (2023). Pain through the perspective of art and creativity: insights from the Unmasking Pain project. Frontiers in Pain Research, 4, Article 1179116. https://doi.org/10.3389/fpain.2023.1179116

People struggle to tell their story of living with pain and when they do it is articulated in a way that may not be understood, heard or taken seriously. Unmasking Pain is an artist-led project that explored creative approaches to tell stories of lif... Read More about Pain through the perspective of art and creativity: insights from the Unmasking Pain project.

Histamine receptors in GtoPdb v.2023.1 (2023)
Journal Article
Chazot, P., Cowart, M., Fukui, H., Ganellin, C. R., Gutzmer, R., Haas, H. L., …Young, J. M. (2023). Histamine receptors in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE, 2023(1), https://doi.org/10.2218/gtopdb/f33/2023.1

Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [80, 174]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [80]. The human and... Read More about Histamine receptors in GtoPdb v.2023.1.