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Outputs (9)

Harnessing epigenetic variability for crop improvement: current status and future prospects (2021)
Journal Article
Kim, E. Y., Kim, K. D., & Cho, J. (2022). Harnessing epigenetic variability for crop improvement: current status and future prospects. Genes & Genomics, 44(3), 259-266. https://doi.org/10.1007/s13258-021-01189-7

Background
The epigenetic mechanisms play critical roles in a vast diversity of biological processes of plants, including development and response to environmental challenges. Particularly, DNA methylation is a stable epigenetic signature that suppl... Read More about Harnessing epigenetic variability for crop improvement: current status and future prospects.

Phase separation of chromatin and small RNA pathways in plants (2021)
Journal Article
Lei, Z., Wang, L., Kim, E. Y., & Cho, J. (2021). Phase separation of chromatin and small RNA pathways in plants. The Plant Journal, 108(5), 1256-1265. https://doi.org/10.1111/tpj.15517

Gene expression can be modulated by epigenetic mechanisms, including chromatin modifications and small regulatory RNAs. These pathways are unevenly distributed within a cell and usually take place in specific intracellular regions. Unfortunately, the... Read More about Phase separation of chromatin and small RNA pathways in plants.

Ribosome stalling and SGS3 phase separation prime the epigenetic silencing of transposons (2021)
Journal Article
Kim, E. Y., Wang, L., Lei, Z., Li, H., Fan, W., & Cho, J. (2021). Ribosome stalling and SGS3 phase separation prime the epigenetic silencing of transposons. Nature Plants, 7(3), 303-309. https://doi.org/10.1038/s41477-021-00867-4

Transposable elements (TEs, transposons) are mobile DNAs that can cause fatal mutations1. To suppress their activity, host genomes deploy small interfering RNAs (siRNAs) that trigger and maintain their epigenetic silencing2,3. Whereas 24-nucleotide (... Read More about Ribosome stalling and SGS3 phase separation prime the epigenetic silencing of transposons.

Recent advancement of NGS technologies to detect active transposable elements in plants (2021)
Journal Article
Satheesh, V., Fan, W., Chu, J., & Cho, J. (2021). Recent advancement of NGS technologies to detect active transposable elements in plants. Genes & Genomics, 43(3), 289-294. https://doi.org/10.1007/s13258-021-01040-z

Unlike peoples’ belief that transposable elements (TEs) are “junk DNAs” or “genomic parasites”, TEs are essential genomic elements that bring about genetic diversity and enable evolution of a species. In fact, transposons are major constituent of chr... Read More about Recent advancement of NGS technologies to detect active transposable elements in plants.