Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7
(2020)
Journal Article
Ye, F., Kotta-Loizou, I., Jovanovic, M., Liu, X., Dryden, D. T., Buck, M., & Zhang, X. (2020). Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7. eLife, 9, Article e52125. https://doi.org/10.7554/elife.52125
Bacteriophage T7 infects Escherichia coli and evades the host restriction/modification system. The Ocr protein of T7 was shown to exist as a dimer mimicking DNA and to bind to host restriction enzymes, thus preventing the degradation of the viral gen... Read More about Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7.