Outputs (4)

Mice deficient in involucrin, envoplakin and periplakin have a defective epidermal barrier (2007)
Journal Article
Sevilla, L., Nachat, R., Groot, K., Klement, J., Uitto, J., Djian, P., …Watt, F. (2007). Mice deficient in involucrin, envoplakin and periplakin have a defective epidermal barrier. Journal of Cell Biology, 179(7), 1599-1612. https://doi.org/10.1083/jcb.200706187

The cornified envelope is assembled from transglutaminase cross-linked proteins and lipids in the outermost epidermal layers and is essential for skin barrier function. Involucrin, envoplakin, and periplakin form the protein scaffold on which the env... Read More about Mice deficient in involucrin, envoplakin and periplakin have a defective epidermal barrier.

Cytolinker Cross-talk: Periplakin N-terminus Interacts with Plectin to Regulate Keratin Organisation and Epithelial Migration (2007)
Journal Article
Boczonadi, V., McInroy, L., & Maatta, A. (2007). Cytolinker Cross-talk: Periplakin N-terminus Interacts with Plectin to Regulate Keratin Organisation and Epithelial Migration. Experimental Cell Research, 313(16), 3579-3591. https://doi.org/10.1016/j.yexcr.2007.07.005

Periplakin is a cytoskeletal linker protein that participates in the assembly of epidermal cell cornified envelope and regulates keratin organisation in simple epithelial cells. We have generated a stably transfected MCF-7 subclone expressing HA-tagg... Read More about Cytolinker Cross-talk: Periplakin N-terminus Interacts with Plectin to Regulate Keratin Organisation and Epithelial Migration.

Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion (2007)
Journal Article
McInroy, L., & Maatta, A. (2007). Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion. Biochemical and Biophysical Research Communications, 360(1), 109-114. https://doi.org/10.1016/j.bbrc.2007.06.036

Vimentin is a type III Intermediate filament protein that is expressed frequently in epithelial carcinomas correlating with invasiveness and poor prognosis. We have analysed migration and adhesion to collagenous matrix of a panel of carcinoma cell li... Read More about Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion.

Ectopic expression of syndecan-1 in basal epidermis affects keratinocyte proliferation and wound re-epithelialization (2007)
Journal Article
Ojeh, N., Hiilesvuo, K., Wärri, A., Salmivirta, M., Henttinen, T., & Maatta, A. (2007). Ectopic expression of syndecan-1 in basal epidermis affects keratinocyte proliferation and wound re-epithelialization. Journal of Investigative Dermatology, 128(1), 26-34. https://doi.org/10.1038/sj.jid.5700967

Epidermal proliferation and differentiation can be regulated by soluble morphogens and growth factors. Heparan sulfate proteoglycans (HSPGs) modulate the action of several of these effector molecules, such as members of the fibroblast growth factor (... Read More about Ectopic expression of syndecan-1 in basal epidermis affects keratinocyte proliferation and wound re-epithelialization.