Outputs (65)

Exploiting protein modification systems to boost crop productivity: SUMO proteases in focus (2018)
Journal Article
Garrido, E., Srivastava, A. K., & Sadanandom, A. (2018). Exploiting protein modification systems to boost crop productivity: SUMO proteases in focus. Journal of Experimental Botany, 69(19), 4625-4632. https://doi.org/10.1093/jxb/ery222

In recent years, post-translational modification (PTM) of proteins has emerged as a key process that integrates plant growth and response to a changing environment. During the processes of domestication and breeding, plants were selected for various... Read More about Exploiting protein modification systems to boost crop productivity: SUMO proteases in focus.

Post-translational modifications in priming the plant immune system: ripe for exploitation? (2018)
Journal Article
De Vega, D., Newton, A. C., & Sadanandom, A. (2018). Post-translational modifications in priming the plant immune system: ripe for exploitation?. FEBS Letters, 592(12), 1929-1936. https://doi.org/10.1002/1873-3468.13076

Microbes constantly challenge plants, and some can successfully infect their host and cause disease. Basal immunity against plant pathogens in many cases is not enough for survival and leads to disease and, ultimately, a premature death of the host p... Read More about Post-translational modifications in priming the plant immune system: ripe for exploitation?.

Fifty shades of SUMO: its role in immunity and at the fulcrum of the growth-defence balance (2018)
Journal Article
Verma, V., Croley, F., & Sadanandom, A. (2018). Fifty shades of SUMO: its role in immunity and at the fulcrum of the growth-defence balance. Molecular Plant Pathology, 19(6), 1537-1544. https://doi.org/10.1111/mpp.12625

The sessile nature of plants requires them to cope with an ever‐changing environment. Effective adaptive responses require sophisticated cellular mechanisms at the post‐transcriptional and post‐translational levels. Post‐translational modification by... Read More about Fifty shades of SUMO: its role in immunity and at the fulcrum of the growth-defence balance.

BTB-BACK Domain Protein POB1 Suppresses Immune Cell Death by Targeting Ubiquitin E3 ligase PUB17 for Degradation (2017)
Journal Article
Orosa, B., He, Q., Mesmar, J., Gilroy, E. M., McLellan, H., Yang, C., …Sadanandom, A. (2017). BTB-BACK Domain Protein POB1 Suppresses Immune Cell Death by Targeting Ubiquitin E3 ligase PUB17 for Degradation. PLoS Genetics, 13(1), Article e1006540. https://doi.org/10.1371/journal.pgen.1006540

Hypersensitive response programmed cell death (HR-PCD) is a critical feature in plant immunity required for pathogen restriction and prevention of disease development. The precise control of this process is paramount to cell survival and an effective... Read More about BTB-BACK Domain Protein POB1 Suppresses Immune Cell Death by Targeting Ubiquitin E3 ligase PUB17 for Degradation.

SUMO Is a Critical Regulator of Salt Stress Responses in Rice (2016)
Journal Article
Srivastava, A. K., Zhang, C., Yates, G., Bailey, M., Brown, A., & Sadanandom, A. (2016). SUMO Is a Critical Regulator of Salt Stress Responses in Rice. Plant Physiology, 170, 2378-2391. https://doi.org/10.1104/pp.15.01530

SUMO (Small Ubiquitin-like Modifier) conjugation onto target proteins has emerged as a very influential class of protein modification systems. SUMO1/2 double mutant plants are nonviable, underlining the importance of SUMO conjugation to plant surviva... Read More about SUMO Is a Critical Regulator of Salt Stress Responses in Rice.

Stability of small ubiquitin-like modifier (SUMO) proteases OVERLY TOLERANT TO SALT1 and -2 modulates salicylic acid signalling and SUMO1/2 conjugation in Arabidopsis thaliana (2015)
Journal Article
Bailey, M., Srivastava, A., Conti, L., Nelis, S., Zhang, C., Florance, H., …Sadanandom, A. (2016). Stability of small ubiquitin-like modifier (SUMO) proteases OVERLY TOLERANT TO SALT1 and -2 modulates salicylic acid signalling and SUMO1/2 conjugation in Arabidopsis thaliana. Journal of Experimental Botany, 67(1), 353-363. https://doi.org/10.1093/jxb/erv468

Small ubiquitin-like modifier proteases 1 and 2 (SUMO1/2) have been linked to the regulation of salicylic acid (SA)-mediated defence signalling in Arabidopsis thaliana. In order to define the role of the SUMO proteases OVERLY TOLERANT TO SALT1 and -2... Read More about Stability of small ubiquitin-like modifier (SUMO) proteases OVERLY TOLERANT TO SALT1 and -2 modulates salicylic acid signalling and SUMO1/2 conjugation in Arabidopsis thaliana.

SUMOylation of phytochrome-B negatively regulates light-induced signaling in Arabidopsis thaliana (2015)
Journal Article
Sadanandom, A., Ádám, É., Orosa, B., Viczián, A., Klose, C., Zhang, C., …Nagy, F. (2015). SUMOylation of phytochrome-B negatively regulates light-induced signaling in Arabidopsis thaliana. Proceedings of the National Academy of Sciences, 112(35), 11108-11113. https://doi.org/10.1073/pnas.1415260112

The red/far red light absorbing photoreceptor phytochrome-B (phyB) cycles between the biologically inactive (Pr, λmax, 660 nm) and active (Pfr; λmax, 730 nm) forms and functions as a light quality and quantity controlled switch to regulate photomorph... Read More about SUMOylation of phytochrome-B negatively regulates light-induced signaling in Arabidopsis thaliana.

Structure and Mechanism of Dimer-Monomer Transition of a Plant Poly(A)-Binding Protein upon RNA Interaction: Insights into Its Poly(A) Tail Assembly (2015)
Journal Article
Domingues, M., Sforça, M., Soprano, A., Lee, J., Campos Brasil de Souza, T. D. A., Cassago, A., …Benedetti, C. (2015). Structure and Mechanism of Dimer-Monomer Transition of a Plant Poly(A)-Binding Protein upon RNA Interaction: Insights into Its Poly(A) Tail Assembly. Journal of Molecular Biology, 427(15), 2491-2506. https://doi.org/10.1016/j.jmb.2015.05.017

Poly(A)-binding proteins (PABPs) play crucial roles in mRNA biogenesis, stability, transport and translational control in most eukaryotic cells. Although animal PABPs are well-studied proteins, the biological role, three-dimensional structure and RNA... Read More about Structure and Mechanism of Dimer-Monomer Transition of a Plant Poly(A)-Binding Protein upon RNA Interaction: Insights into Its Poly(A) Tail Assembly.

U-box E3 ubiquitin ligase PUB17 acts in the nucleus to promote specific immune pathways triggered by Phytophthora infestans (2015)
Journal Article
He, Q., McLellan, H., Boevink, P., Sadanandom, A., Xie, C., Birch, P., & Tian, Z. (2015). U-box E3 ubiquitin ligase PUB17 acts in the nucleus to promote specific immune pathways triggered by Phytophthora infestans. Journal of Experimental Botany, 66(11), 3189-3199. https://doi.org/10.1093/jxb/erv128

Ubiquitination regulates many processes in plants, including immunity. The E3 ubiquitin ligase PUB17 is a positive regulator of programmed cell death (PCD) triggered by resistance proteins CF4/9 in tomato. Its role in immunity to the potato late blig... Read More about U-box E3 ubiquitin ligase PUB17 acts in the nucleus to promote specific immune pathways triggered by Phytophthora infestans.

Destabilization of interaction between cytokinin signaling intermediates AHP1 and ARR4 modulates Arabidopsis development (2015)
Journal Article
Verma, V., Sivaraman, J., Srivastava, A., Sadanandom, A., & Kumar, P. (2015). Destabilization of interaction between cytokinin signaling intermediates AHP1 and ARR4 modulates Arabidopsis development. New Phytologist, 206(2), 726-737. https://doi.org/10.1111/nph.13297

Eukaryotic two-component signaling involves the His–Asp–His–Asp multistep phosphorelay (MSP). In Arabidopsis thaliana, cytokinin-mediated MSP signaling intermediates include histidine kinases (HKs), histidine phosphotransfer proteins (Hpts) and respo... Read More about Destabilization of interaction between cytokinin signaling intermediates AHP1 and ARR4 modulates Arabidopsis development.