Outputs (4)

Intraoperative doppler velocity measurements to locate patent ITA grafts at reoperation (2006)
Journal Article
Lotto, A., & Owens, W. (2006). Intraoperative doppler velocity measurements to locate patent ITA grafts at reoperation. The Annals of Thoracic Surgery, 82(3), 1108-1110. https://doi.org/10.1016/j.athoracsur.2006.01.036

We are reporting a case of a patient who underwent an aortic valve replacement with previous coronary artery bypass grafting. During the operation we used a Doppler velocity probe to locate the exact position of the bilateral internal thoracic arteri... Read More about Intraoperative doppler velocity measurements to locate patent ITA grafts at reoperation.

Sustained augmentation of cardiac 1A-adrenergic drive results in pathological remodeling with contractile dysfunction, progressive fibrosis and reactivation of matricellular protein genes (2006)
Journal Article
Chaulet, H., Lin, F., Guo, J., Owens, W., Michalicek, J., Kesteven, S., …Graham, R. (2006). Sustained augmentation of cardiac 1A-adrenergic drive results in pathological remodeling with contractile dysfunction, progressive fibrosis and reactivation of matricellular protein genes. Journal of Molecular and Cellular Cardiology, 40(4), 540-552. https://doi.org/10.1016/j.yjmcc.2006.01.015

We previously reported that transgenic (TG) mice with cardiac-restricted α1A-adrenergic receptor (α1A-AR)-overexpression showed enhanced contractility, but no hypertrophy. Since chronic inotropic enhancement may be deleterious, we investigated if lon... Read More about Sustained augmentation of cardiac 1A-adrenergic drive results in pathological remodeling with contractile dysfunction, progressive fibrosis and reactivation of matricellular protein genes.

Targeted inactivation of Gh/transglutaminase II (2001)
Journal Article
Nanda, N., Iismaa, S., Owens, W., Husain, A., Mackay, F., & Graham, R. (2001). Targeted inactivation of Gh/transglutaminase II. Journal of Biological Chemistry, 276(23), 20673-20678. https://doi.org/10.1074/jbc.m010846200

The novel G-protein, Gh/tissue transglutaminase (TGase II), has both guanosine triphosphatase and Ca2+-activated transglutaminase activity and has been implicated in a number of processes including signal transduction, apoptosis, bone ossification, w... Read More about Targeted inactivation of Gh/transglutaminase II.

A policy of elective delayed sternal closure does not improve the outcome following arterial switch (2001)
Journal Article
Owens, W., Vitale, N., Hasan, A., & Hamilton, J. (2001). A policy of elective delayed sternal closure does not improve the outcome following arterial switch. The Annals of Thoracic Surgery, 71(5), 1553-1555. https://doi.org/10.1016/s0003-4975%2801%2902395-5

Background. Delayed sternal closure is regularly used in the immediate management of hemodynamic instability after neonatal cardiac procedures. The aim of this study was to assess whether the routine, elective use of delayed sternal closure would red... Read More about A policy of elective delayed sternal closure does not improve the outcome following arterial switch.