Activation of the unfolded protein response and alternative splicing of ATF6α in HLA-B27 positive lymphocytes
(2007)
Journal Article
Lemin, A., Saleki, K., van Lith, M., & Benham, A. (2007). Activation of the unfolded protein response and alternative splicing of ATF6α in HLA-B27 positive lymphocytes. FEBS Letters, 581(9), 1819-1824. https://doi.org/10.1016/j.febslet.2007.03.069
Misfolding of major histocompatibility complex (MHC) class I molecules has been implicated in the rheumatic autoimmune disease ankylosing spondylitis (AS), and has been linked to the unfolded protein response (UPR) in rodent AS models. XBP1 and ATF6α... Read More about Activation of the unfolded protein response and alternative splicing of ATF6α in HLA-B27 positive lymphocytes.