Outputs (2)

A Glycopolymer Sensor Array That Differentiates Lectins and Bacteria (2024)
Journal Article
Leslie, K. G., Jolliffe, K. A., Müllner, M., New, E. J., Turnbull, W. B., Fascione, M. A., Friman, V.-P., & Mahon, C. S. (2024). A Glycopolymer Sensor Array That Differentiates Lectins and Bacteria. Biomacromolecules, 25(11), 7466-7474. https://doi.org/10.1021/acs.biomac.4c01129

Identification of bacterial lectins offers an attractive route to the development of new diagnostics, but the design of specific sensors is complicated by the low selectivity of carbohydrate-lectin interactions. Here we describe a glycopolymer-based... Read More about A Glycopolymer Sensor Array That Differentiates Lectins and Bacteria.

Sugar-Coated: Can Multivalent Glycoconjugates Improve upon Nature’s Design? (2024)
Journal Article
Leslie, K. G., Berry, S. S., Miller, G. J., & Mahon, C. S. (2024). Sugar-Coated: Can Multivalent Glycoconjugates Improve upon Nature’s Design?. Journal of the American Chemical Society, 146(40), 27215-27232. https://doi.org/10.1021/jacs.4c08818

Multivalent interactions between receptors and glycans play an important role in many different biological processes, including pathogen infection, self-recognition, and the immune response. The growth in the number of tools and techniques toward the... Read More about Sugar-Coated: Can Multivalent Glycoconjugates Improve upon Nature’s Design?.