Outputs (2)

Understanding hormonal crosstalk in Arabidopsis root development via emulation and history matching (2020)
Journal Article
Jackson, S., Vernon, I., Liu, J., & Lindsey, K. (2020). Understanding hormonal crosstalk in Arabidopsis root development via emulation and history matching. Statistical Applications in Genetics and Molecular Biology, 19(2), Article 20180053. https://doi.org/10.1515/sagmb-2018-0053

A major challenge in plant developmental biology is to understand how plant growth is coordinated by interacting hormones and genes. To meet this challenge, it is important to not only use experimental data, but also formulate a mathematical model. F... Read More about Understanding hormonal crosstalk in Arabidopsis root development via emulation and history matching.

Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions (2018)
Journal Article
Vernon, I., Liu, J., Goldstein, M., Rowe, J., Topping, J., & Lindsey, K. (2018). Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions. BMC systems biology, 12, Article 1. https://doi.org/10.1186/s12918-017-0484-3

Many mathematical models have now been employed across every area of systems biology. These models increasingly involve large numbers of unknown parameters, have complex structure which can result in substantial evaluation time relative to the needs... Read More about Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions.