Outputs (2)

Pore-forming toxins (2012)
Book Chapter
Iacovache, I., Degiacomi, M., & van der Goot, F. (2012). Pore-forming toxins. In E. H. Egelman (Ed.), Comprehensive biophysics (164-188). Elsevier. https://doi.org/10.1016/b978-0-12-374920-8.00518-x

Pore forming toxins are proteins capable of inserting pores in the membranes of the target cells which in turn may lead to the lysis of the cell and release of nutrients. The mechanism by which the pore-forming toxins (PFTs) function during a bacteri... Read More about Pore-forming toxins.

Arranged sevenfold: Structural insights into the C-terminal oligomerization domain of human C4b-binding protein. (2012)
Journal Article
Hofmeyer, T., Schmelz, S., Degiacomi, M., Dal Peraro, M., Daneschdar, M., Scrima, A., …Kolmar, H. (2013). Arranged sevenfold: Structural insights into the C-terminal oligomerization domain of human C4b-binding protein. Journal of Molecular Biology, 425(8), 1302-1317. https://doi.org/10.1016/j.jmb.2012.12.017

The complement system as a major part of innate immunity is the first line of defense against invading microorganisms. Orchestrated by more than 60 proteins, its major task is to discriminate between host cells and pathogens and to initiate immune re... Read More about Arranged sevenfold: Structural insights into the C-terminal oligomerization domain of human C4b-binding protein..