Outputs (2)

Epidermal expression of a sterol biosynthesis gene regulates root growth by a non-cell autonomous mechanism in Arabidopsis (2018)
Journal Article
Short, E., Pullen, M., Imriz, G., Liu, D., Cope-Selby, N., Hetherington, F., …Lindsey, K. (2018). Epidermal expression of a sterol biosynthesis gene regulates root growth by a non-cell autonomous mechanism in Arabidopsis. Development, 145(10), Article dev160572. https://doi.org/10.1242/dev.160572

The epidermis is hypothesized to play a signalling role during plant development. One class of mutants showing defects in signal transduction and radial patterning are those in sterol biosynthesis. The expectation is that living cells require sterols... Read More about Epidermal expression of a sterol biosynthesis gene regulates root growth by a non-cell autonomous mechanism in Arabidopsis.

Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions (2018)
Journal Article
Vernon, I., Liu, J., Goldstein, M., Rowe, J., Topping, J., & Lindsey, K. (2018). Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions. BMC systems biology, 12, Article 1. https://doi.org/10.1186/s12918-017-0484-3

Many mathematical models have now been employed across every area of systems biology. These models increasingly involve large numbers of unknown parameters, have complex structure which can result in substantial evaluation time relative to the needs... Read More about Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions.