Skip to main content

Research Repository

Advanced Search

Outputs (279)

Drug Mimetic Organogelators for the Control of Concomitant Crystallization of Barbital and Thalidomide (2020)
Journal Article

A strategic approach to control the polymorphism of two related drugs by introducing a drug-mimetic imide functional group into the molecular weight organogelator structure is presented. This was achieved with novel aminoglutethimide-derived bis(urea... Read More about Drug Mimetic Organogelators for the Control of Concomitant Crystallization of Barbital and Thalidomide.

Oligomer/polymer blend phase diagram and surface concentration profiles for squalane/polybutadiene: experimental measurements and predictions from SAFT-g Mie and molecular dynamics simulations (2020)
Journal Article

The compatibility and surface behavior of squalane–polybutadiene mixtures are studied by experimental cloud point and neutron reflectivity measurements, statistical associating fluid theory (SAFT), and molecular dynamics (MD) simulations. A SAFT-γ Mi... Read More about Oligomer/polymer blend phase diagram and surface concentration profiles for squalane/polybutadiene: experimental measurements and predictions from SAFT-g Mie and molecular dynamics simulations.

Site-specific phosphorylation and caspase cleavage of GFAP are new markers of Alexander Disease severity (2019)
Journal Article

Alexander Disease (AxD) is a fatal neurodegenerative disorder caused by mutations in glial fibrillary acidic protein (GFAP), which supports the structural integrity of astrocytes. Over 70 GFAP missense mutations cause AxD, but the mechanism linking d... Read More about Site-specific phosphorylation and caspase cleavage of GFAP are new markers of Alexander Disease severity.