Outputs (1330)

Allophycocyanin A is a carbon dioxide receptor in the cyanobacterial phycobilisome (2022)
Journal Article
Guillen-Garcia, A., Gibson, S., Jordan, C., Ramaswamy, V., Linthwaite, V., Bromley, E., …Cann, M. (2022). Allophycocyanin A is a carbon dioxide receptor in the cyanobacterial phycobilisome. Nature Communications, 13, Article 5289. https://doi.org/10.1038/s41467-022-32925-6

Light harvesting is fundamental for production of ATP and reducing equivalents for CO2 fixation during photosynthesis. However, electronic energy transfer (EET) through a photosystem can harm the photosynthetic apparatus when not balanced with CO2. H... Read More about Allophycocyanin A is a carbon dioxide receptor in the cyanobacterial phycobilisome.

Towards Intelligently Designed Evolvable Processors (2022)
Journal Article
Jones, B. A., Chouard, J. L., Branco, B. C., Vissol-Gaudin, E. G., Pearson, C., Petty, M. C., …Groves, C. (2022). Towards Intelligently Designed Evolvable Processors. Evolutionary Computation, 30(4), 479-501. https://doi.org/10.1162/evco_a_00309

Evolution-in-Materio is a computational paradigm in which an algorithm reconfigures a material’s properties to achieve a specific computational function. This paper addresses the question of how successful and well performing Evolution-in-Materio pro... Read More about Towards Intelligently Designed Evolvable Processors.

Molecular simulation approaches to the study of thermotropic and lyotropic liquid crystals (2022)
Journal Article
Wilson, M. R., Yu, G., Potter, T. D., Walker, M., Gray, S. J., Li, J., & Boyd, N. J. (2022). Molecular simulation approaches to the study of thermotropic and lyotropic liquid crystals. Crystals, 12(5), Article 685. https://doi.org/10.3390/cryst12050685

Over the last decade, the availability of computer time, together with new algorithms capable of exploiting parallel computer architectures, has opened up many possibilities in molecularly modelling liquid crystalline systems. This perspective articl... Read More about Molecular simulation approaches to the study of thermotropic and lyotropic liquid crystals.

How does location determine the economic competitiveness of grid-scale Emerging PV? (2022)
Journal Article
Nieto-Díaz, B. A., Crossland, A. F., & Groves, C. (2022). How does location determine the economic competitiveness of grid-scale Emerging PV?. Energy Technology, 10(5), Article 2101012. https://doi.org/10.1002/ente.202101012

Emerging Photovoltaic (PV) devices with perovskite or organic absorber layers may play a substantial role in our energy future due to their potential low-cost manufacture and differing properties compared to established Silicon equivalents. However,... Read More about How does location determine the economic competitiveness of grid-scale Emerging PV?.

Mechanical Compaction of Crustal Analogs Made of Sintered Glass Beads: The Influence of Porosity and Grain Size (2021)
Journal Article
Carbillet, L., Heap, M. J., Baud, P., Wadsworth, F. B., & Reuschlé, T. (2021). Mechanical Compaction of Crustal Analogs Made of Sintered Glass Beads: The Influence of Porosity and Grain Size. Journal of Geophysical Research. Solid Earth, 126(4), Article e2020JB021321. https://doi.org/10.1029/2020jb021321

The fundamentals of our understanding of the mechanical compaction of porous rocks stem from experimental studies. Yet, many of these studies use natural materials for which microstructural parameters are intrinsically coupled, hampering the diagnosi... Read More about Mechanical Compaction of Crustal Analogs Made of Sintered Glass Beads: The Influence of Porosity and Grain Size.

Anion-Responsive Fluorescent Supramolecular Gels (2022)
Journal Article
Picci, G., Mulvee, M. T., Caltagirone, C., Lippolis, V., Frontera, A., Gomila, R. M., & Steed, J. W. (2022). Anion-Responsive Fluorescent Supramolecular Gels. Molecules, 27(4), Article 1257. https://doi.org/10.3390/molecules27041257

Three novel bis-urea fluorescent low-molecular-weight gelators (LMWGs) based on the tetraethyl diphenylmethane spacer—namely, L1, L2, and L3, bearing indole, dansyl, and quinoline units as fluorogenic fragments, respectively, are able to form gel in... Read More about Anion-Responsive Fluorescent Supramolecular Gels.

Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP (2022)
Journal Article
Quinlan, P. R., Figeuredo, G., Mongan, N., Jordan, L. B., Bray, S. E., Sreseli, R., …Quinlan, R. A. (2022). Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP. Cell Stress and Chaperones, 27(2), 177-188. https://doi.org/10.1007/s12192-022-01258-0

Our cluster analysis of the Cancer Genome Atlas for co-expression of HSP27 and CRYAB in breast cancer patients identified three patient groups based on their expression level combination (high HSP27+low CRYAB; low HSP27+high CRYAB; similar HSP27+CRYA... Read More about Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP.

Development of a setup to characterize capillary liquid bridges between liquid infused surfaces (2022)
Journal Article
Goodband, S. J., Kusumaatmaja, H., & Voïtchovsky, K. (2022). Development of a setup to characterize capillary liquid bridges between liquid infused surfaces. AIP Advances, 12(1), Article 015120. https://doi.org/10.1063/5.0072548

Capillary liquid bridges are ubiquitous in nature and are present in many industrial processes. In order to model their behavior, it is essential to develop suitable experimental tools that are able to characterize the bridges’ geometry and the assoc... Read More about Development of a setup to characterize capillary liquid bridges between liquid infused surfaces.

A Tale of Two Bioconjugations: pH Controlled Divergent Reactivity of Protein α-oxo-Aldehydes in Competing α-oxo-Mannich and Catalyst-Free Aldol Ligations (2021)
Journal Article
Keenan, T., Spears, R. J., Akkad, S., Mahon, C. S., Hatton, N. E., Walton, J., …Fascione, M. A. (2021). A Tale of Two Bioconjugations: pH Controlled Divergent Reactivity of Protein α-oxo-Aldehydes in Competing α-oxo-Mannich and Catalyst-Free Aldol Ligations. ACS Chemical Biology, 16(11), 2387-2400. https://doi.org/10.1021/acschembio.1c00531

Site-selective chemical methods for protein bioconjugation have revolutionized the fields of cell and chemical biology through the development of novel protein/enzyme probes bearing fluorescent, spectroscopic, or even toxic cargos. Herein, we report... Read More about A Tale of Two Bioconjugations: pH Controlled Divergent Reactivity of Protein α-oxo-Aldehydes in Competing α-oxo-Mannich and Catalyst-Free Aldol Ligations.

Structure and hydration of polyvinylpyrrolidone-hydrogen peroxide (2021)
Journal Article
Chambers, L. I., Yufit, D. S., Fox, M. A., Musa, O. M., & Steed, J. W. (2022). Structure and hydration of polyvinylpyrrolidone-hydrogen peroxide. Chemical Communications, 58(1), 80-83. https://doi.org/10.1039/d1cc06047c

The structure of the commercially important polyvinylpyrrolidone-hydrogen peroxide complex can be understood by reference to the co-crystal structure of a hydrogen peroxide complex and its mixed hydrates of a two-monomer unit model compound, bisVP·2H... Read More about Structure and hydration of polyvinylpyrrolidone-hydrogen peroxide.

Enhancement of sensitivity for dichlorvos detection by a low-weight gelator based on bolaamphiphile amino acid derivatives decorated with a hybrid graphene quantum dot/enzyme/hydrogel (2021)
Journal Article
Sahub, C., Andrews, J. L., Smith, J. P., Mohamad Arif, M. A., Tomapatanaget, B., & Steed, J. W. (2021). Enhancement of sensitivity for dichlorvos detection by a low-weight gelator based on bolaamphiphile amino acid derivatives decorated with a hybrid graphene quantum dot/enzyme/hydrogel. Materials Chemistry Frontiers, 5(18), 6850-6859. https://doi.org/10.1039/d1qm00296a

Developing the sensitivity of an optical biosensor motivates the exploration of an amplification strategy for the incorporation of a biosensor system in a supramolecular hydrogel. We developed novel fluorescent hybrid materials comprising graphene qu... Read More about Enhancement of sensitivity for dichlorvos detection by a low-weight gelator based on bolaamphiphile amino acid derivatives decorated with a hybrid graphene quantum dot/enzyme/hydrogel.

Tuning the Bulk and Surface Properties of PDMS Networks through Cross-Linker and Surfactant Concentration (2021)
Journal Article
Litwinowicz, M., Rogers, S., Caruana, A., Kinane, C., Tellam, J., & Thompson, R. (2021). Tuning the Bulk and Surface Properties of PDMS Networks through Cross-Linker and Surfactant Concentration. Macromolecules, 54(20), https://doi.org/10.1021/acs.macromol.1c01600

The elastic modulus and hydrophilicity of cross-linked poly(dimethylsiloxane) (PDMS) are tunable via cross-linker concentration and the addition of a simple surfactant, C12E4, before curing. However, the surfactant concentration, [C12E4], reduces the... Read More about Tuning the Bulk and Surface Properties of PDMS Networks through Cross-Linker and Surfactant Concentration.

A Novel Dynamic Hysteresis Model for Grain-Oriented Electrical Steels Based on Magnetic Domain Theory (2021)
Journal Article
Zhang, Z., Hamzehbahmani, H., & Gaskell, P. H. (2022). A Novel Dynamic Hysteresis Model for Grain-Oriented Electrical Steels Based on Magnetic Domain Theory. IEEE Transactions on Magnetics, 58(1), 1-9. https://doi.org/10.1109/tmag.2021.3128765

A novel approach is adopted to model the hysteresis phenomenon of grain-oriented electrical steels (GOESs), by incorporating a variation of the domain patterns associated with ferromagnetic materials during magnetization and demagnetization. The ensu... Read More about A Novel Dynamic Hysteresis Model for Grain-Oriented Electrical Steels Based on Magnetic Domain Theory.

Permeability of packs of polydisperse hard spheres (2021)
Journal Article
Vasseur, J., Wadsworth, F. B., Coumans, J. P., & Dingwell, D. B. (2021). Permeability of packs of polydisperse hard spheres. Physical Review E, 103(6), https://doi.org/10.1103/physreve.103.062613

The permeability of packs of spheres is important in a wide range of physical scenarios. Here, we create numerically generated random periodic domains of spheres that are polydisperse in size and use lattice-Boltzmann simulations of fluid flow to det... Read More about Permeability of packs of polydisperse hard spheres.

A hybrid ensemble learning-based prediction model to minimize delay in air cargo transport using bagging and stacking (2021)
Journal Article
Sahoo, R., Pasayat, A., Bhowmick, B., Fernandes, K., & Tiwari, M. (2022). A hybrid ensemble learning-based prediction model to minimize delay in air cargo transport using bagging and stacking. International Journal of Production Research, 60(2), 644-660. https://doi.org/10.1080/00207543.2021.2013563

Manufacturing productivity is inextricably linked to air freight handling for the global delivery of finished and semi-finished goods. In this article, our focus is to capture the transport risk associated with air freight which is the difference bet... Read More about A hybrid ensemble learning-based prediction model to minimize delay in air cargo transport using bagging and stacking.

The force required to operate the plunger on a French press (2021)
Journal Article
Wadsworth, F. B., Vossen, C. E., Heap, M. J., Kushnir, A., Farquharson, J. I., Schmid, D., …Kendrick, J. E. (2021). The force required to operate the plunger on a French press. American Journal of Physics, 89, Article 769. https://doi.org/10.1119/10.0004224

The French press is a popular device for brewing coffee, comprising a cylindrical beaker—or “jug”—fitted with a lid and plunger with a fine wire mesh filter. The plunger is used to drive the solid coffee particles to the bottom of the jug, separating... Read More about The force required to operate the plunger on a French press.

Pathogenic variants in the CYP21A2 gene cause isolated autosomal dominant congenital posterior polar cataracts (2021)
Journal Article
Berry, V., Pontikos, N., Ionides, A., Kalitzeos, A., Quinlan, R. A., & Michaelides, M. (2022). Pathogenic variants in the CYP21A2 gene cause isolated autosomal dominant congenital posterior polar cataracts. Ophthalmic Genetics, 43(2), 218-223. https://doi.org/10.1080/13816810.2021.1998556

Background: Congenital cataracts are the most common cause of visual impairment worldwide. Inherited cataract is a clinically and genetically heterogeneous disease. Here we report disease-causing variants in a novel gene, CYP21A2, causing autosomal d... Read More about Pathogenic variants in the CYP21A2 gene cause isolated autosomal dominant congenital posterior polar cataracts.

Gravity-driven film flow down a uniformly heated smoothly corrugated rigid substrate (2021)
Journal Article
Daly, G., Veremieiev, S., & Gaskell, P. (2022). Gravity-driven film flow down a uniformly heated smoothly corrugated rigid substrate. Journal of Fluid Mechanics, 930, Article A23. https://doi.org/10.1017/jfm.2021.920

Gravity induced film flow over a rigid smoothly corrugated substrate heated uniformly from below, is explored. This is achieved by reducing the governing equations of motion and energy conservation to a manageable form within the mathematical framewo... Read More about Gravity-driven film flow down a uniformly heated smoothly corrugated rigid substrate.

The importance of the epithelial fibre cell interface to lens regeneration in an in vivo rat model and in a human bag-in-the-lens (BiL) sample (2021)
Journal Article
Wu, W., Lois, N., Prescott, A. R., Brown, A. P., Van Gerwen, V., Tassignon, M., …Quinlan, R. A. (2021). The importance of the epithelial fibre cell interface to lens regeneration in an in vivo rat model and in a human bag-in-the-lens (BiL) sample. Experimental Eye Research, 213, Article 108808. https://doi.org/10.1016/j.exer.2021.108808

Human lens regeneration and the Bag-in-the-Lens (BIL) surgical treatment for cataract both depend upon lens capsule closure for their success. Our studies suggest that the first three days after surgery are critical to their long-term outcomes. Using... Read More about The importance of the epithelial fibre cell interface to lens regeneration in an in vivo rat model and in a human bag-in-the-lens (BiL) sample.

Derisking the Polymorph Landscape: The Complex Polymorphism of Mexiletine Hydrochloride (2021)
Journal Article
Andrews, J. L., Nilsson Lill, S. O., Freitag-Pohl, S., Apperley, D. C., Yufit, D. S., Batsanov, A. S., …Steed, J. W. (2021). Derisking the Polymorph Landscape: The Complex Polymorphism of Mexiletine Hydrochloride. Crystal Growth and Design, 21(12), 7150-7167. https://doi.org/10.1021/acs.cgd.1c01009

This work presents an updated solid form discovery approach to the polymorphism of the anti-arrhythmic drug mexiletine hydrochloride, in which experimental and computational techniques are combined to provide a rigorous characterisation of the solid-... Read More about Derisking the Polymorph Landscape: The Complex Polymorphism of Mexiletine Hydrochloride.