Outputs (2)

Glutamatergic dysfunction leads to a hyper-dopaminergic phenotype through deficits in short-term habituation: a mechanism for aberrant salience (2022)
Journal Article

Psychosis in disorders like schizophrenia is commonly associated with aberrant salience and elevated striatal dopamine. However, the underlying cause(s) of this hyper-dopaminergic state remain elusive. Various lines of evidence point to glutamatergic... Read More about Glutamatergic dysfunction leads to a hyper-dopaminergic phenotype through deficits in short-term habituation: a mechanism for aberrant salience.

Reinforcement rate and the balance between excitatory and inhibitory learning: insights from deletion of the GluA1 AMPA receptor subunit (2022)
Journal Article

Conditioned responding is sensitive to reinforcement rate. This rate-sensitivity is impaired in genetically modified mice that lack the GluA1 subunit of the AMPA receptor. A time-dependent application of the Rescorla–Wagner learning rule can be used... Read More about Reinforcement rate and the balance between excitatory and inhibitory learning: insights from deletion of the GluA1 AMPA receptor subunit.