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Outputs (4)

Phenotypic changes associated with deletion and overexpression of a stage-regulated gene family in Leishmania (2001)
Journal Article
McKean, P., Denny, P., Knuepfer, E., Keen, J., & Smith, D. (2001). Phenotypic changes associated with deletion and overexpression of a stage-regulated gene family in Leishmania. Cellular Microbiology, 3(8), 511-523. https://doi.org/10.1046/j.1462-5822.2001.00135.x

The LmcDNA16 locus of Leishmania major contains three highly related genes HASPA1, HASPA2 and HASPB, encoding hydrophilic, acylated surface proteins and a tandem pair of unrelated sequences, SHERP1 and SHERP2, coding for a small, hydrophilic protein... Read More about Phenotypic changes associated with deletion and overexpression of a stage-regulated gene family in Leishmania.

GPI-anchored proteins and glycoconjugates segregate into lipid rafts in Kinetoplastida (2001)
Journal Article
Denny, P., Field, M., & Smith, D. (2001). GPI-anchored proteins and glycoconjugates segregate into lipid rafts in Kinetoplastida. FEBS Letters, 491(1-2), 148-153. https://doi.org/10.1016/s0014-5793%2801%2902172-x

The plasma membranes of the divergent eukaryotic parasites, Leishmania and Trypanosoma, are highly specialised, with a thick coat of glycoconjugates and glycoproteins playing a central role in virulence. Unusually, the majority of these surface macro... Read More about GPI-anchored proteins and glycoconjugates segregate into lipid rafts in Kinetoplastida.

The in vivo conformation of the Plastid DNA of Toxoplasma gondii: Implications for replication (2001)
Journal Article
Williamson, D., Denny, P., Moore, P., Sato, S., McCready, S., & Wilson, R. (2001). The in vivo conformation of the Plastid DNA of Toxoplasma gondii: Implications for replication. Journal of Molecular Biology, 306(2), 159-168. https://doi.org/10.1006/jmbi.2000.4385

The Phylum Apicomplexa comprises thousands of obligate intracellular parasites, some of which cause serious disease in man and other animals. Though not photosynthetic, some of them, including the malaria parasites (Plasmodium spp.) and the causative... Read More about The in vivo conformation of the Plastid DNA of Toxoplasma gondii: Implications for replication.