Cryo-EM structures of the human Elongator complex at work
(2024)
Journal Article
Abbassi, N., Jaciuk, M., Scherf, D., Böhnert, P., Rau, A., Hammermeister, A., …Glatt, S. (2024). Cryo-EM structures of the human Elongator complex at work. Nature Communications, 15(1), Article 4094. https://doi.org/10.1038/s41467-024-48251-y
tRNA modifications affect ribosomal elongation speed and co-translational folding dynamics. The Elongator complex is responsible for introducing 5-carboxymethyl at wobble uridine bases (cm5U34) in eukaryotic tRNAs. However, the structure and function... Read More about Cryo-EM structures of the human Elongator complex at work.