All Outputs (3505)

The effect of additive aggregation state on controlling crystallization. Crystallization of L-asparagine monohydrate in the presence of carboxylic acid functionality additives
Journal Article
Cooper, S. (online). The effect of additive aggregation state on controlling crystallization. Crystallization of L-asparagine monohydrate in the presence of carboxylic acid functionality additives. CrystEngComm, art. no.-56

L-Asparagine monohydrate crystals grown from 100-300% supersaturated solutions in the presence of 1-20 mg ml(-1) polyacrylic acid exhibit a needle-like morphology, instead of their normal prismatic morphology. A similar effect is observed for crystal... Read More about The effect of additive aggregation state on controlling crystallization. Crystallization of L-asparagine monohydrate in the presence of carboxylic acid functionality additives.

NMR and chiroptical examination of the diastereoisomers of (S)-Eu-EOB-DTPA
Journal Article
Thompson, N., Parker, D., Schmitt-Willich, H., Sulzle, D., Muller, G., & Riehl, J. (online). NMR and chiroptical examination of the diastereoisomers of (S)-Eu-EOB-DTPA. Dalton Transactions, 1892-1895

The solution structure of the diastereoisomers of (S)-Eu-EOB-DTPA has been analysed by H-1 NMR, CD and CPL spectroscopy. Two major species exist which possess very similar 1H NMR paramagnetic shifts and emission spectra, consistent with a 9-coordinat... Read More about NMR and chiroptical examination of the diastereoisomers of (S)-Eu-EOB-DTPA.

Synthesis of a europium complex for anion-sensing involving regioselective substitution of cyclen
Journal Article
Yu, J., & Parker, D. (online). Synthesis of a europium complex for anion-sensing involving regioselective substitution of cyclen. European Journal of Organic Chemistry, 4249-4252

A regioselective synthetic route that allows the construction of tri-functionally substituted cyclen is described. This facilitates the synthesis of a europium complex that exhibits a good photoresponse to malate, forming the basis of a chemoselectiv... Read More about Synthesis of a europium complex for anion-sensing involving regioselective substitution of cyclen.

An improved synthesis and structural characterisation of 2-(4-acetylthiophenylethynyl)-4-nitro-5-phenylethynylaniline: The molecule showing high negative differential resistance (NDR)
Journal Article
Wang, C., Batsanov, A., Bryce, M., & Sage, I. (online). An improved synthesis and structural characterisation of 2-(4-acetylthiophenylethynyl)-4-nitro-5-phenylethynylaniline: The molecule showing high negative differential resistance (NDR). Synthesis: Journal of Synthetic Organic Chemistry, 2089-2095

2-(4-Acetylthiophenylethynyl)-4-nitro-5-phenyl-ethynylaniline (11) has been synthesised by an improved route, which has many advantages over the literature procedure. A key intermediate is 2-ethynyl-4-nitro-5-phenylethynylaniline (6) which is obtaine... Read More about An improved synthesis and structural characterisation of 2-(4-acetylthiophenylethynyl)-4-nitro-5-phenylethynylaniline: The molecule showing high negative differential resistance (NDR).

Polyene natural products
Journal Article
Thirsk, C., & Whiting, A. (online). Polyene natural products. Journal of the Chemical Society. Perkin transactions 1, 999-1023

Synthesis and luminescence properties of a kinetically stable dinuclear ytterbium complex with differentiated binding sites
Journal Article
Pope, S., Kenwright, A., Heath, S., & Faulkner, S. (online). Synthesis and luminescence properties of a kinetically stable dinuclear ytterbium complex with differentiated binding sites. Chemical Communications, 1550-1551

The complex Yb2L contains two DO3A units separated by a phenol bridging group and gives time-resolved luminescence spectra in solution consistent with the presence of two types of binding site.

Practical syntheses of N-hexylcarbazol-2-yl- and -3-yl-boronic acids, their cross-coupled products and a derived tris-cyclometalated (pyridin-2-yl)carbazole iridium(III) complex
Journal Article
Tavasli, M., Bettington, S., Bryce, M., Batsanov, A., & Monkman, A. (online). Practical syntheses of N-hexylcarbazol-2-yl- and -3-yl-boronic acids, their cross-coupled products and a derived tris-cyclometalated (pyridin-2-yl)carbazole iridium(III) complex. Synthesis: Journal of Synthetic Organic Chemistry, 1619-1624

The syntheses of N-hcxylcarbazol-2-yl- and -3-yl-boronic acids (1 and 2) are described on a ca. 7 g scale, starting from commercially available 2,5-dibromonitrobenzene (4) and carbazole (11), respectively. Compounds I and 2 underwent efficient pallad... Read More about Practical syntheses of N-hexylcarbazol-2-yl- and -3-yl-boronic acids, their cross-coupled products and a derived tris-cyclometalated (pyridin-2-yl)carbazole iridium(III) complex.

New shelf-stable halo- and alkoxy-substituted pyridylboronic acids and their Suzuki cross-coupling reactions to yield heteroarylpyridines
Journal Article
Parry, P., Bryce, M., & Tarbit, B. (online). New shelf-stable halo- and alkoxy-substituted pyridylboronic acids and their Suzuki cross-coupling reactions to yield heteroarylpyridines. Synthesis: Journal of Synthetic Organic Chemistry, 1035-1038

New shelf-stable pyridylboronic acids have been synthesized: bromine-lithium exchange followed by reaction with triiso-propylborate (TEPB) yielded 2-fluoro-5-pyridylboronic acid (4), 3-bromo-5-pyridylboronic acid (5) and 2-ethoxy-5-pyridylboronic aci... Read More about New shelf-stable halo- and alkoxy-substituted pyridylboronic acids and their Suzuki cross-coupling reactions to yield heteroarylpyridines.

The Design, Synthesis and Characterisation of Channel-Forming Peptides
Journal Article
Sanderson, J., & Yazdani, S. (online). The Design, Synthesis and Characterisation of Channel-Forming Peptides. Chemical Communications, 1154-1155. https://doi.org/10.1039/b203046b

Synthetic peptides designed using criteria derived from statistical analyses of beta-barrel membrane proteins form channels in synthetic membranes at very low peptide:lipid ratios.

A novel scandium ortho-methoxynitrosobenzene-dimer complex: mechanistic implications for the nitroso-Diels-Alder reaction
Journal Article
Lightfoot, A., Pritchard, R., Wan, H., Warren, J., & Whiting, A. (online). A novel scandium ortho-methoxynitrosobenzene-dimer complex: mechanistic implications for the nitroso-Diels-Alder reaction. Chemical Communications, 2072-2073

Arylnitroso dienophiles exist in equilibrium with their dimeric counterparts, which in turn form stable bidentate complexes with scandium(III) triflate and react with cyclohexadiene to give the corresponding Diels-Alder adduct at the same rate as the... Read More about A novel scandium ortho-methoxynitrosobenzene-dimer complex: mechanistic implications for the nitroso-Diels-Alder reaction.

The development and application of ruthenium catalysed oxidations of a hydroxamic acid and in situ Diels-Alder trapping of the acyl nitroso derivative
Journal Article
Flower, K., Lightfoot, A., Wan, H., & Whiting, A. (online). The development and application of ruthenium catalysed oxidations of a hydroxamic acid and in situ Diels-Alder trapping of the acyl nitroso derivative. Journal of the Chemical Society. Perkin transactions 1, 2058-2064

Ruthenium(II) complexes can be used to oxidise N-Boc-hydroxylamine in the presence of tert-butyl hydroperoxide (TBHP) to the corresponding nitroso dienophile, which is trapped by cyclohexa-1,3-diene as the hetero-Diels-Alder adduct. Direct evidence h... Read More about The development and application of ruthenium catalysed oxidations of a hydroxamic acid and in situ Diels-Alder trapping of the acyl nitroso derivative.

The oxidative addition of a chlorophosphine to Pd-0: formation and characterisation of a 42-electron triangulo palladium cluster
Journal Article
Dyer, P., Fawcett, J., Hanton, M., Mingos, D., & Williamson, A. (online). The oxidative addition of a chlorophosphine to Pd-0: formation and characterisation of a 42-electron triangulo palladium cluster. Dalton Transactions, 2400-2401

The reactions that lead to the formation of the 42-electron cluster [PdCl{P(NPr2i)(2)}](3) from various sources of the {P(NPr2i)(2)} moiety are investigated, and the structure of the triangulo cluster confirmed by X-ray crystallography.

Efficient relaxivity enhancement in dendritic gadolinium complexes: effective motional coupling in medium molecular weight conjugates
Journal Article
Fulton, D., O'Halloran, M., Parker, D., Senanayake, K., Botta, M., & Aime, S. (online). Efficient relaxivity enhancement in dendritic gadolinium complexes: effective motional coupling in medium molecular weight conjugates. Chemical Communications, 474-476

Enhancement of the relaxivities of Gd-based MRI contrast agents is achieved by placing the metal ion at the barycentre of the molecular complex in order to improve motional coupling.

The first genuine observation of fluorescent mononuclear phthalocyanine aggregates
Journal Article
Farren, C., FitzGerald, S., Beeby, A., & Bryce, M. (online). The first genuine observation of fluorescent mononuclear phthalocyanine aggregates. Chemical Communications, 572-573

An initial photophysical study of a tetra-solketal-substituted zinc phthalocyanine is reported; at low temperature this compound exhibits very strong aggregation, and a new red shifted emission peak is observed, lambda(max) approximate to750 nm, attr... Read More about The first genuine observation of fluorescent mononuclear phthalocyanine aggregates.

Synthesis and characterisation of the new oxyselenide Bi2YO4Cu2Se2
Journal Article
Evans, J., Brogden, E., Thompson, A., & Cordiner, R. (online). Synthesis and characterisation of the new oxyselenide Bi2YO4Cu2Se2. Chemical Communications, 912-913

In this communication we report the synthesis, structure and preliminary characterisation of Bi(2)LnO(4)Cu(2)Se(2) (Ln = Y, Gd, Sm, Nd, La) phases; these materials are members of a new family of layered oxychalcogenides.

Steric control of lanthanide hydration state: fast water exchange at gadolinium in a mono-amide 'DOTA' complex
Journal Article
Congreve, A., Parker, D., Gianolio, E., & Botta, M. (online). Steric control of lanthanide hydration state: fast water exchange at gadolinium in a mono-amide 'DOTA' complex. Dalton Transactions, 1441-1445

Detailed analyses of the solution structure and exchange dynamics of two sets of homologous mono-amide triacetate lanthanide complexes (Ln = Eu, Gd) of cyclen have been undertaken. The complex [LnL(1)], bearing an N-linked CH2CH2NHCO-pyridyl moiety,... Read More about Steric control of lanthanide hydration state: fast water exchange at gadolinium in a mono-amide 'DOTA' complex.

Electrochemically controlled interactions between TTF-based dendrimers and an electron-rich oligomer
Journal Article
Beeby, A., Bryce, M., Christensen, C., Cooke, G., Duclairoir, F., & Rotello, V. (online). Electrochemically controlled interactions between TTF-based dendrimers and an electron-rich oligomer. Chemical Communications, 2950-2951

Electrochemically controlled interactions have been shown to occur between TTF containing dendrimers 1 and 2 and the electron-rich oligomer 3.

Influence of hydrogen bonding on coordination polymer assembly
Journal Article
Applegarth, L., Goeta, A., & Steed, J. (online). Influence of hydrogen bonding on coordination polymer assembly. Chemical Communications, 2405-2406

An extended dipyridyl ligand (L-1) capable of hydrogen bonding with guest species via urea functionalities has been designed and synthesised. Assembly of a silver(I) coordination polymer of L-1 is dependent on the nature of the hydrogen bond acceptor... Read More about Influence of hydrogen bonding on coordination polymer assembly.

Highly emissive, nine-coordinate enantiopure lanthanide complexes incorporating tetraazatriphenylenes as probes for DNA
Journal Article
Bobba, G., Frias, J., & Parker, D. (online). Highly emissive, nine-coordinate enantiopure lanthanide complexes incorporating tetraazatriphenylenes as probes for DNA. Chemical Communications, 890-891

The interaction of q = 0 Delta- and Lambda-Tb and Eu complexes with poly(dAdT), poly(dGdC) and calf-thymus DNA has been examined by absorption, emission and chiroptical spectroscopy and is sensitive to complex helicity, base-pair type and the nature... Read More about Highly emissive, nine-coordinate enantiopure lanthanide complexes incorporating tetraazatriphenylenes as probes for DNA.

Platinum catalysed 3,4- and 1,4-diboration of alpha,beta-unsaturated carbonyl compounds using bis-pinacolatodiboron
Journal Article
Bell, N., Cox, A., Cameron, N., Evans, J., Marder, T., Duin, M., Elsevier, C., Baucherel, X., Tulloch, A., & Tooze, R. (online). Platinum catalysed 3,4- and 1,4-diboration of alpha,beta-unsaturated carbonyl compounds using bis-pinacolatodiboron. Chemical Communications, 1854-1855

Bis-pinacolatodiboron reacts with alpha,beta-unsaturated carbonyl compounds to give 1,4- and unprecedented 3,4-additions in the presence of a second generation Pt(0) catalyst at ambient temperature.