Low affinity binding site clusters confer HOX specificity and regulatory robustness
(2015)
Journal Article
Crocker, J., Abe, N., Rinaldi, L., McGregor, A., Frankel, N., Wang, S., …Stern, D. (2015). Low affinity binding site clusters confer HOX specificity and regulatory robustness. Cell, 160(1-2), 191-203. https://doi.org/10.1016/j.cell.2014.11.041
All Outputs (156)
Genetic architecture and functional characterization of genes underlying the rapid diversification of male external genitalia between Drosophila simulans and Drosophila mauritiana (2015)
Journal Article
Tanaka, K., Hopfen, C., Herbert, M., Schlötterer, C., Stern, D., Masly, J., …Nunes, M. (2015). Genetic architecture and functional characterization of genes underlying the rapid diversification of male external genitalia between Drosophila simulans and Drosophila mauritiana. Genetics, 200(1), 357-369. https://doi.org/10.1534/genetics.114.174045
Time-series transcriptomics reveals that AGAMOUS-LIKE22 affects primary metabolism and developmental processes in drought-stressed arabidopsis (2015)
Journal Article
Bechtold, U., Penfold, C., Jenkins, D., Legaie, R., Moore, J., Lawson, T., …Mullineaux, P. (2015). Time-series transcriptomics reveals that AGAMOUS-LIKE22 affects primary metabolism and developmental processes in drought-stressed arabidopsis. The Plant Cell, 28(2), 345-366. https://doi.org/10.1105/tpc.15.00910
The evolution and expression of panarthropod frizzled genes (2015)
Journal Article
Janssen, R., Schönauer, A., Weber, M., Turetzek, N., Hogvall, M., Goss, G., …Hilbrant, M. (2015). The evolution and expression of panarthropod frizzled genes. Frontiers in Ecology and Evolution, 3(AUG), https://doi.org/10.3389/fevo.2015.00096
Global effects of land use on local terrestrial biodiversity (2015)
Journal Article
Newbold, T., Hudson, L., Hill, S., Contu, S., Lysenko, I., Senior, R., …Purvis, A. (2015). Global effects of land use on local terrestrial biodiversity. Nature, 520(7545), 45-50. https://doi.org/10.1038/nature14324
Metal toxicity and the p53 protein: An intimate relationship (2015)
Journal Article
Phatak, V., & Muller, P. (2015). Metal toxicity and the p53 protein: An intimate relationship. https://doi.org/10.1039/c4tx00117f
Flowering locus C’s lessons: Conserved chromatin switches underpinning developmental timing and adaptation (2015)
Journal Article
Hepworth, J., & Dean, C. (2015). Flowering locus C’s lessons: Conserved chromatin switches underpinning developmental timing and adaptation. Plant Physiology, 168(4), 1237-1245. https://doi.org/10.1104/pp.15.00496
Climate changes in the central Mediterranean and Italian vegetation dynamics since the Pliocene (2015)
Journal Article
Combourieu_Nebout, N., Bertini, A., Russo-Ermolli, E., Peyron, O., Klotz, S., Montade, V., …Sadori, L. (2015). Climate changes in the central Mediterranean and Italian vegetation dynamics since the Pliocene. Review of Palaeobotany and Palynology, 218, https://doi.org/10.1016/j.revpalbo.2015.03.001
From shavenbaby to the naked valley: Trichome formation as a model for evolutionary developmental biology (2015)
Journal Article
Arif, S., Kittelmann, S., & Mcgregor, A. (2015). From shavenbaby to the naked valley: Trichome formation as a model for evolutionary developmental biology. Evolution & Development, 17(1), 120-126. https://doi.org/10.1111/ede.12113
Functional interplay between MDM2, p63/p73 and mutant p53 (2015)
Journal Article
Stindt, M., Muller, P., Ludwig, R., Kehrloesser, S., Dötsch, V., & Vousden, K. (2015). Functional interplay between MDM2, p63/p73 and mutant p53. Oncogene, 34(33), 4300-4310. https://doi.org/10.1038/onc.2014.359
c-Met and other cell surface molecules: Interaction, activation and functional consequences (2015)
Journal Article
Viticchiè, G., & Muller, P. (2015). c-Met and other cell surface molecules: Interaction, activation and functional consequences. Biomedicines, 3(1), 46-70. https://doi.org/10.3390/biomedicines3010046
Hybridization due to changing species distributions: adding problems or solutions to conservation of biodiversity during global change? (2015)
Journal Article
Brennan, A. C., Woodward, G., Seehausen, O., Munoz-Fuentes, V., Moritz, C., Guelmami, A., …Edelaar, P. (2015). Hybridization due to changing species distributions: adding problems or solutions to conservation of biodiversity during global change?. Evolutionary Ecology Research, 16(6), 475-491Background: Due to increasing global change, the rate of hybridization appears to be increasing. Question: Is hybridization adding problems or solutions to the effects of global change on biodiversity? Methods: We divided ourselves into two independe... Read More about Hybridization due to changing species distributions: adding problems or solutions to conservation of biodiversity during global change?.
Freshwater and coastal migration patterns in the silver-stage eel Anguilla anguilla (2015)
Journal Article
Barry, J., Newton, M., Dodd, J., Lucas, M., Boylan, P., & Adams, C. (2016). Freshwater and coastal migration patterns in the silver-stage eel Anguilla anguilla. Journal of Fish Biology, 88(2), 676-689. https://doi.org/10.1111/jfb.12865The unimpeded downstream movement patterns and migration success of small female and male Anguilla anguilla through a catchment in north-west Europe were studied using an acoustic hydrophone array along the River Finn and into the Foyle Estuary in Ir... Read More about Freshwater and coastal migration patterns in the silver-stage eel Anguilla anguilla.
Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium (2015)
Journal Article
Mardaryev, A., Liu, B., Rapisarda, V., Poterlowicz, K., Malashchuk, I., Rudolf, J., …Botchkarev, V. (2016). Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. Journal of Cell Biology, 212(1), 77-89. https://doi.org/10.1083/jcb.201506065During development, multipotent progenitor cells establish lineage-specific programmers of gene activation and silencing underlying their differentiation into specialized cell types. We show that the Polycomb component Cbx4 serves as a critical deter... Read More about Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium.
Phosphorylation Regulates the Endocytic Function of the Yeast Dynamin-Related Protein Vps1 (2015)
Journal Article
Smaczynska-de Rooij, I. I., Marklew, C. J., Allwood, E. G., Palmer, S. E., Booth, W. I., Mishra, R., …Ayscough, K. R. (2016). Phosphorylation Regulates the Endocytic Function of the Yeast Dynamin-Related Protein Vps1. Molecular and Cellular Biology, 36(5), 742-755. https://doi.org/10.1128/mcb.00833-15The family of dynamin proteins is known to function in many eukaryotic membrane fusion and fission events. The yeast dynamin-related protein Vps1 functions at several stages of membrane trafficking, including Golgi apparatus to endosome and vacuole,... Read More about Phosphorylation Regulates the Endocytic Function of the Yeast Dynamin-Related Protein Vps1.
Maternal Oxytocin Is Linked to Close Mother-Infant Proximity in Grey Seals (Halichoerus grypus) (2015)
Journal Article
Robinson, K. J., Twiss, S. D., Hazon, N., & Pomeroy, P. P. (2015). Maternal Oxytocin Is Linked to Close Mother-Infant Proximity in Grey Seals (Halichoerus grypus). PLoS ONE, 10(12), Article e0144577. https://doi.org/10.1371/journal.pone.0144577Maternal behaviour is a crucial component of reproduction in all mammals; however the quality of care that mothers give to infants can vary greatly. It is vital to document variation in maternal behaviour caused by the physiological processes control... Read More about Maternal Oxytocin Is Linked to Close Mother-Infant Proximity in Grey Seals (Halichoerus grypus).
Hypercapnia modulates cAMP signalling and cystic fibrosis transmembrane conductance regulator-dependent anion and fluid secretion in airway epithelia (2015)
Journal Article
Turner, M., Saint-Crib, V., Patel, W., Ibrahim, S., Verdon, B., Ward, C., …Gray, M. (2016). Hypercapnia modulates cAMP signalling and cystic fibrosis transmembrane conductance regulator-dependent anion and fluid secretion in airway epithelia. The Journal of Physiology, 594(6), 1643-1661. https://doi.org/10.1113/jp271309Hypercapnia is clinically defined as an arterial blood partial pressure of CO2 of above 40 mmHg and is a feature of chronic lung disease. In previous studies we have demonstrated that hypercapnia modulates agonist-stimulated cAMP levels through effec... Read More about Hypercapnia modulates cAMP signalling and cystic fibrosis transmembrane conductance regulator-dependent anion and fluid secretion in airway epithelia.
Identification of MEDIATOR16 as the Arabidopsis COBRA suppressor, MONGOOSE1 (2015)
Journal Article
Sorek, N., Szemenyei, H., Sorek, H., Landers, A., Knight, H., Bauer, S., …Somerville, D. (2015). Identification of MEDIATOR16 as the Arabidopsis COBRA suppressor, MONGOOSE1. Proceedings of the National Academy of Sciences, 112(52), 16048-16053. https://doi.org/10.1073/pnas.1521675112We performed a screen for genetic suppressors of cobra, an Arabidopsis mutant with defects in cellulose formation and an increased ratio of unesterified/esterified pectin. We identified a suppressor named mongoose1 (mon1) that suppressed the growth d... Read More about Identification of MEDIATOR16 as the Arabidopsis COBRA suppressor, MONGOOSE1.
Land sparing, land sharing, and the fate of Africa's lions (2015)
Journal Article
Stephens, P. (2015). Land sparing, land sharing, and the fate of Africa's lions. Proceedings of the National Academy of Sciences, 112(48), 14753-14754. https://doi.org/10.1073/pnas.1520709112Taxonomic bias in organismal research and conservation is well recognized, with focus disproportionately directed toward birds and mammals (1). Among mammals, carnivores often receive excessive attention and large carnivores are particularly well stu... Read More about Land sparing, land sharing, and the fate of Africa's lions.
Advances in 3D cell culture technologies enabling tissue-like structures to be created in vitro (2015)
Journal Article
Knight, E., & Przyborski, S. (2015). Advances in 3D cell culture technologies enabling tissue-like structures to be created in vitro. Journal of Anatomy, 227(6), 746-756. https://doi.org/10.1111/joa.12257Research in mammalian cell biology often relies on developing in vitro models to enable the growth of cells in the laboratory to investigate a specific biological mechanism or process under different test conditions. The quality of such models and ho... Read More about Advances in 3D cell culture technologies enabling tissue-like structures to be created in vitro.