Bypass of activation loop phosphorylation by aspartate 836 in activation of the endoribonuclease activity of Ire1
(2017)
Journal Article
Armstrong, M., Sestak, S., Ali, A., Sagini, H., Brown, M., Baty, K., …Schröder, M. (2017). Bypass of activation loop phosphorylation by aspartate 836 in activation of the endoribonuclease activity of Ire1. Molecular and Cellular Biology, 37(16), e00655-16. https://doi.org/10.1128/mcb.00655-16
The bifunctional protein kinase-endoribonuclease Ire1 initiates splicing of the mRNA for the transcription factor Hac1 when unfolded proteins accumulate in the endoplasmic reticulum. Activation of Saccharomyces cerevisiae Ire1 coincides with autophos... Read More about Bypass of activation loop phosphorylation by aspartate 836 in activation of the endoribonuclease activity of Ire1.