Phage Orf family recombinases: conservation of activities and involvement of the central channel in DNA binding

Curtis, F.A.; Malay, A.D.; Trotter, A.J.; Wilson, L.A.; Barradell-Black, M.M.; Bowers, L.Y.; Reed, P.; Hillyar, C.R.T.; Yeo, R.P.; Sanderson, J.M.; Heddle, J.G.; Sharples, G.J.

doi:10.1371/journal.pone.0102454

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Phage Orf family recombinases: conservation of activities and involvement of the central channel in DNA binding (2014)
Journal Article
Curtis, F., Malay, A., Trotter, A., Wilson, L., Barradell-Black, M., Bowers, L., …Sharples, G. (2014). Phage Orf family recombinases: conservation of activities and involvement of the central channel in DNA binding. PLoS ONE, 9(8), Article e102454. https://doi.org/10.1371/journal.pone.0102454

Genetic and biochemical evidence suggests that λ Orf is a recombination mediator, promoting nucleation of either bacterial RecA or phage Redβ recombinases onto single-stranded DNA (ssDNA) bound by SSB protein. We have identified a diverse family of O... Read More about Phage Orf family recombinases: conservation of activities and involvement of the central channel in DNA binding.