The Design, Synthesis and Characterisation of Channel-Forming Peptides

Sanderson, J.M.; Yazdani, S.

doi:10.1039/b203046b

All Outputs (4)

Characterisation of the Interactions of Aromatic Amino Acids with Diacetyl Phosphatidylcholine (2004)
Journal Article
Sanderson, J., & Whelan, E. (2004). Characterisation of the Interactions of Aromatic Amino Acids with Diacetyl Phosphatidylcholine. Physical Chemistry Chemical Physics, 6(5), 1012-1017. https://doi.org/10.1039/b312184d

A simple bimolecular system for characterising the interactions of amino acids with diacyl-3-phosphatidylcholines has been developed. The system contains two components: an N-acetyl amino acid N'-alkyl amide and diacetyl-3-sn-phosphatidylcholine (DAP... Read More about Characterisation of the Interactions of Aromatic Amino Acids with Diacetyl Phosphatidylcholine.

The Synthesis of Peptides and Proteins Containing Non-Natural Amino Acids (2004)
Journal Article
Hodgson, D., & Sanderson, J. (2004). The Synthesis of Peptides and Proteins Containing Non-Natural Amino Acids. Chemical Society Reviews, 33(7), 422-430. https://doi.org/10.1039/b312953p

Methods for the incorporation of non-natural amino acids into proteins have advanced significantly over recent years and in this tutorial review we aim to give a general overview of the area. These techniques offer the possibility of modulating the s... Read More about The Synthesis of Peptides and Proteins Containing Non-Natural Amino Acids.

Analysis of Liposomal Membrane Composition Using Raman Tweezers (2004)
Journal Article
Sanderson, J., & Ward, A. (2004). Analysis of Liposomal Membrane Composition Using Raman Tweezers. Chemical Communications, 1120-1121. https://doi.org/10.1039/b316757g

We have developed a methodology for the analysis of liposomal membranes and their contents using near-IR Raman spectroscopy on liposomes held in an optical trap. We were able to detect a variety of membrane components including lipids, cholesterol, a... Read More about Analysis of Liposomal Membrane Composition Using Raman Tweezers.

The Design, Synthesis and Characterisation of Channel-Forming Peptides (2004)
Journal Article
Sanderson, J., & Yazdani, S. (2004). The Design, Synthesis and Characterisation of Channel-Forming Peptides. Chemical Communications, 1154-1155. https://doi.org/10.1039/b203046b

Synthetic peptides designed using criteria derived from statistical analyses of beta-barrel membrane proteins form channels in synthetic membranes at very low peptide:lipid ratios.