All Outputs (2)

Glycosylated nanoparticles as efficient antimicrobial delivery agents (2016)
Journal Article
Eissa, A., Abdulkarim, A., Sharples, G., & Cameron, N. (2016). Glycosylated nanoparticles as efficient antimicrobial delivery agents. Biomacromolecules, 17(8), 2672-2679. https://doi.org/10.1021/acs.biomac.6b00711

Synthetic polymer nanoparticles that can be tailored through multivalent ligand display on the surface, while at the same time allowing encapsulation of desired bioactive molecules, are especially useful in providing a versatile and robust platform i... Read More about Glycosylated nanoparticles as efficient antimicrobial delivery agents.

Mycobacterium tuberculosis RuvX is a Holliday junction resolvase formed by dimerisation of the monomeric YqgF nuclease domain (2016)
Journal Article
Nautiyal, A., Rani, P., Sharples, G., & Muniyappa, K. (2016). Mycobacterium tuberculosis RuvX is a Holliday junction resolvase formed by dimerisation of the monomeric YqgF nuclease domain. Molecular Microbiology, 100(4), 656-674. https://doi.org/10.1111/mmi.13338

The Mycobacterium tuberculosis genome possesses homologues of the ruvC and yqgF genes that encode putative Holliday junction (HJ) resolvases. However, their gene expression profiles and enzymatic properties have not been experimentally defined. Here... Read More about Mycobacterium tuberculosis RuvX is a Holliday junction resolvase formed by dimerisation of the monomeric YqgF nuclease domain.