All Outputs (5)

A randomised controlled trial of prehabilitation in patients undergoing elective cardiac surgery (2023)
Journal Article
Akowuah, E., Wagnild, J., Bardgett, M., Prichard, J., Mathias, A., Harrison, S., …Maier, R. (2023). A randomised controlled trial of prehabilitation in patients undergoing elective cardiac surgery. Anaesthesia: Peri-operative medicine, critical care and pain, 78(9), 1120-1128. https://doi.org/10.1111/anae.16072

The feasibility, safety and efficacy of prehabilitation in adult patients awaiting elective cardiac surgery are unknown. A total of 180 participants undergoing elective cardiac surgery were allocated randomly to receive either standard pre-operative... Read More about A randomised controlled trial of prehabilitation in patients undergoing elective cardiac surgery.

Minithoracotomy vs Conventional Sternotomy for Mitral Valve Repair (2023)
Journal Article
Akowuah, E. F., Maier, R. H., Hancock, H. C., Kharatikoopaei, E., Vale, L., Fernandez-Garcia, C., …Khan, H. (2023). Minithoracotomy vs Conventional Sternotomy for Mitral Valve Repair. Journal of the American Medical Association, 329(22), https://doi.org/10.1001/jama.2023.7800

Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction (2023)
Journal Article
Bawamia, B., Spray, L., Wangsaputra, V. K., Bennaceur, K., Vahabi, S., Stellos, K., …Spyridopoulos, I. (2023). Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction. GeroScience, 45(4), 2689-2705. https://doi.org/10.1007/s11357-023-00794-6

Myocardial infarction (MI) accelerates immune ageing characterised by lymphopenia, expansion of terminally differentiated CD8+ T-lymphocytes (CD8+ TEMRA) and inflammation. Pre-clinical data showed that TA-65, an oral telomerase activator, reduced imm... Read More about Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction.

Adapted suicide safety plans to address self-harm, suicidal ideation, and suicide behaviours in autistic adults: protocol for a pilot randomised controlled trial (2023)
Journal Article
Rodgers, J., Goodwin, J., Nielsen, E., Bhattarai, N., Heslop, P., Kharatikoopaei, E., …Cassidy, S. (2023). Adapted suicide safety plans to address self-harm, suicidal ideation, and suicide behaviours in autistic adults: protocol for a pilot randomised controlled trial. Pilot and Feasibility Studies, 9(1), Article 31. https://doi.org/10.1186/s40814-023-01264-8

Background: Suicide prevention is a national priority for the UK government. Autistic people are at greater risk of experiencing self-harm and suicidal thoughts and behaviours than the general population. Safety plans are widely used in suicide preve... Read More about Adapted suicide safety plans to address self-harm, suicidal ideation, and suicide behaviours in autistic adults: protocol for a pilot randomised controlled trial.

Prehabilitation in elective patients undergoing cardiac surgery: a randomised control trial (THE PrEPS TRIAL) – a study protocol (2023)
Journal Article
Akowuah, E., Mathias, A., Bardgett, M., Harrison, S., Kasim, A. S., Loughran, K., …Maier, R. H. (2023). Prehabilitation in elective patients undergoing cardiac surgery: a randomised control trial (THE PrEPS TRIAL) – a study protocol. BMJ Open, 13(1), Article e065992. https://doi.org/10.1136/+bmjopen-2022-065992

Introduction: Prehabilitation prior to surgery has been shown to reduce postoperative complications, reduce length of hospital stay and improve quality of life after cancer and limb reconstruction surgery. However, there are minimal data on the impac... Read More about Prehabilitation in elective patients undergoing cardiac surgery: a randomised control trial (THE PrEPS TRIAL) – a study protocol.