All Outputs (2)

Toxin release by conditional remodelling of ParDE1 from Mycobacterium tuberculosis leads to gyrase inhibition (2023)
Journal Article
Beck, I. N., Arrowsmith, T. J., Grobbelaar, M. J., Bromley, E. C., Marles-Wright, J., & Blower, T. R. (2024). Toxin release by conditional remodelling of ParDE1 from Mycobacterium tuberculosis leads to gyrase inhibition. Nucleic Acids Research, 52(4), 1909-1929. https://doi.org/10.1093/nar/gkad1220

Mycobacterium tuberculosis, the causative agent of tuberculosis, is a growing threat to global health, with recent efforts towards its eradication being reversed in the wake of the COVID-19 pandemic. Increasing resistance to gyrase-targeting second-l... Read More about Toxin release by conditional remodelling of ParDE1 from Mycobacterium tuberculosis leads to gyrase inhibition.

CBT for difficult-to-treat depression: self-regulation model (2023)
Journal Article
Barton, S. B., Armstrong, P. V., Robinson, L. J., & Bromley, E. H. (2023). CBT for difficult-to-treat depression: self-regulation model. Behavioural and Cognitive Psychotherapy, 1-16. https://doi.org/10.1017/s1352465822000273

Background:
Cognitive behavioural therapy (CBT) is an effective treatment for depression but a significant minority of clients do not complete therapy, do not respond to it, or subsequently relapse. Non-responders, and those at risk of relapse, are... Read More about CBT for difficult-to-treat depression: self-regulation model.