Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins
(2024)
Journal Article
Arrowsmith, T. J., Xu, X., Xu, S., Usher, B., Stokes, P., Guest, M., Bronowska, A. K., Genevaux, P., & Blower, T. R. (in press). Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins. Nature Communications, 15(1), Article 7719. https://doi.org/10.1038/s41467-024-51934-1
Nucleotidyltransferases (NTases) control diverse physiological processes, including RNA modification, DNA replication and repair, and antibiotic resistance. The Mycobacterium tuberculosis NTase toxin family, MenT, modifies tRNAs to block translation.... Read More about Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins.