Bacterial sensors define intracellular free energies for correct enzyme metalation

Osman, Deenah; Martini, Maria Alessandra; Foster, Andrew W.; Chen, Junjun; Scott, Andrew J.P.; Morton, Richard J.; Steed, Jonathan W.; Lurie-Luke, Elena; Huggins, Thomas G.; Lawrence, Andrew D.; Deery, Evelyne; Warren, Martin J.; Chivers, Peter T.; Robinson, Nigel J.

doi:10.1038/s41589-018-0211-4

All Outputs (1)

Bacterial sensors define intracellular free energies for correct enzyme metalation (2019)
Journal Article
Osman, D., Martini, M. A., Foster, A. W., Chen, J., Scott, A. J., Morton, R. J., …Robinson, N. J. (2019). Bacterial sensors define intracellular free energies for correct enzyme metalation. Nature Chemical Biology, 15(3), 241-249. https://doi.org/10.1038/s41589-018-0211-4

There is a challenge for metalloenzymes to acquire their correct metals because some inorganic elements form more stable complexes with proteins than do others. These preferences can be overcome provided some metals are more available than others. Ho... Read More about Bacterial sensors define intracellular free energies for correct enzyme metalation.