Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump
(2013)
Journal Article
Janganan, T., Bavro, V., Zhang, L., Borges-Walmsley, M., & Walmsley, A. (2013). Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump. Molecular Microbiology, 88(3), 590-602. https://doi.org/10.1111/mmi.12211
The MtrCDE multidrug pump, from Neisseria gonorrhoeae, is assembled from the inner and outer membrane proteins MtrD and MtrE, which are connected by the periplasmic membrane fusion protein MtrC. Although it is clear that MtrD delivers drugs to the ch... Read More about Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump.