Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate

Mallia, C.J.; Englert, L.; Walter, G.C.; Baxendale, I.R.

Abstract

This short note describes the synthesis of the title compound through spontaneous aerobic oxidation of ethyl 2-phenyl-2-(thiazol-2-yl)acetate. Due to the prevalence of such functional motifs in biologically active substances, we believe the oxidation encountered highlights an important degradation pathway worthy of note.

Citation

Mallia, C., Englert, L., Walter, G., & Baxendale, I. (2015). Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate. Molbank, 2015(2), https://doi.org/10.3390/m857

• Journal Article Type: Article
• Acceptance Date: May 4, 2015
• Publication Date: May 6, 2015
• Deposit Date: May 4, 2015
• Publicly Available Date: Jun 1, 2015
• Journal: Molbank
• Electronic ISSN: 1422-8599
• Publisher: MDPI
• Peer Reviewed: Peer Reviewed
• Volume: 2015
• Issue: 2
• DOI: https://doi.org/10.3390/m857
• Keywords: Thiazole, Oxidation product, Heterocycles.
• Public URL: https://durham-repository.worktribe.com/output/1409068