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Outputs (3)

Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule. (2024)
Journal Article
Kelly, G., Kataura, T., Panek, J., Ma, G., Salmonowicz, H., Davis, A., …Korolchuk, V. I. (2024). Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule. Developmental Cell, Article S1534-5807(24)00295-8. https://doi.org/10.1016/j.devcel.2024.04.020

Selective degradation of damaged mitochondria by autophagy (mitophagy) is proposed to play an important role in cellular homeostasis. However, the molecular mechanisms and the requirement of mitochondrial quality control by mitophagy for cellular phy... Read More about Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule..

Understanding health service utilisation patterns for care home residents during the COVID-19 pandemic using routinely collected healthcare data (2024)
Journal Article
Garner, A., Preston, N., Caiado, C., Stubington, E., Hanratty, B., Limb, J., …Knight, J. (2024). Understanding health service utilisation patterns for care home residents during the COVID-19 pandemic using routinely collected healthcare data. BMC Geriatrics, 24(1), Article 449. https://doi.org/10.1186/s12877-024-05062-6

Background: Healthcare in care homes during the COVID-19 pandemic required a balance, providing treatment while minimising exposure risk. Policy for how residents should receive care changed rapidly throughout the pandemic. A lack of accessible data... Read More about Understanding health service utilisation patterns for care home residents during the COVID-19 pandemic using routinely collected healthcare data.

The impact of digital technology in care homes on unplanned secondary care usage and associated costs. (2024)
Journal Article
Garner, A., Lewis, J., Dixon, S., Preston, N., Caiado, C. C. S., Hanratty, B., …Mason, S. M. (2024). The impact of digital technology in care homes on unplanned secondary care usage and associated costs. Age and Ageing, 53(2), 1-7. https://doi.org/10.1093/ageing/afae004

Background A substantial number of Emergency Department (ED) attendances by care home residents are potentially avoidable. Health Call Digital Care Homes is an app-based technology that aims to streamline residents’ care by recording their observati... Read More about The impact of digital technology in care homes on unplanned secondary care usage and associated costs..