A critical role for iron and zinc homeostatic systems in the evolutionary adaptation of Escherichia coli to metal restriction
(2023)
Journal Article
Paterson, J. R., Wadsworth, J. M., Hu, P., & Sharples, G. J. (2023). A critical role for iron and zinc homeostatic systems in the evolutionary adaptation of Escherichia coli to metal restriction. Microbial Genomics, 9(12), Article 001153. https://doi.org/10.1099/mgen.0.001153
Host nutritional immunity utilizes metal deprivation to help prevent microbial infection. To investigate bacterial adaptation to such restrictive conditions, we conducted experimental evolution with two metal sequestering agents. Ethylenediaminetetra... Read More about A critical role for iron and zinc homeostatic systems in the evolutionary adaptation of Escherichia coli to metal restriction.