Skip to main content

Research Repository

Advanced Search

Outputs (3)

A goodness-of-fit test for the random-effects distribution in mixed models (2017)
Journal Article
Efendi, A., Drikvandi, R., Verbeke, G., & Molenberghs, G. (2017). A goodness-of-fit test for the random-effects distribution in mixed models. Statistical Methods in Medical Research, 26(2), 970-983. https://doi.org/10.1177/0962280214564721

In this paper, we develop a simple diagnostic test for the random-effects distribution in mixed models. The test is based on the gradient function, a graphical tool proposed by Verbeke and Molenberghs to check the impact of assumptions about the rand... Read More about A goodness-of-fit test for the random-effects distribution in mixed models.

Nonlinear mixed-effects models for pharmacokinetic data analysis: assessment of the random-effects distribution (2017)
Journal Article
Drikvandi, R. (2017). Nonlinear mixed-effects models for pharmacokinetic data analysis: assessment of the random-effects distribution. Journal of Pharmacokinetics and Pharmacodynamics, 44(3), 223-232. https://doi.org/10.1007/s10928-017-9510-8

Nonlinear mixed-effects models are frequently used for pharmacokinetic data analysis, and they account for inter-subject variability in pharmacokinetic parameters by incorporating subject-specific random effects into the model. The random effects are... Read More about Nonlinear mixed-effects models for pharmacokinetic data analysis: assessment of the random-effects distribution.