Outputs (2)

Inhibitory Compounds Targeting Plasmodium falciparum Gyrase B (2021)
Journal Article
Pakosz, Z., Lin, T., Michalczyk, E., Nagano, S., & Heddle, J. G. (2021). Inhibitory Compounds Targeting Plasmodium falciparum Gyrase B. Antimicrobial Agents and Chemotherapy, 65(10), https://doi.org/10.1128/aac.00267-21

Malaria persists as a major health problem due to the spread of drug resistance and the lack of effective vaccines. DNA gyrase is a well-validated and extremely effective therapeutic target in bacteria, and it is also known to be present in the apico... Read More about Inhibitory Compounds Targeting Plasmodium falciparum Gyrase B.

Enzyme encapsulation by protein cages (2020)
Journal Article
Chakraborti, S., Lin, T., Glatt, S., & Heddle, J. G. (2020). Enzyme encapsulation by protein cages. RSC Advances, 10(22), 13293-13301. https://doi.org/10.1039/c9ra10983h

Protein cages are hollow protein shells with a nanometric cavity that can be filled with useful materials. The encapsulating nature of the cages means that they are particularly attractive for loading with biological macromolecules, affording the gue... Read More about Enzyme encapsulation by protein cages.