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Outputs (336)

A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit (2024)
Journal Article
Sun, J., Rojo-Cortés, F., Ulian-Benitez, S., Forero, M. G., Li, G., Singh, D., Wang, X., Cachero, S., Moreira, M., Kavanagh, D., Jefferis, G., Croset, V., & Hidalgo, A. (2024). A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit. eLife, 13, Article RP102222. https://doi.org/10.7554/elife.102222.1

Experience shapes the brain, as neural circuits can be modified by neural stimulation or the lack of it. The molecular mechanisms underlying structural circuit plasticity and how plasticity modifies behaviour, are poorly understood. Subjective experi... Read More about A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit.

Mice integrate conspecific and contextual information in forming social episodic-like memories under spontaneous recognition task conditions (2024)
Journal Article
Ross, T. W., Poulter, S. L., Lever, C., & Easton, A. (2024). Mice integrate conspecific and contextual information in forming social episodic-like memories under spontaneous recognition task conditions. Scientific Reports, 14(1), Article 16159. https://doi.org/10.1038/s41598-024-66403-4

The ability to remember unique past events (episodic memory) may be an evolutionarily conserved function, with accumulating evidence of episodic-(like) memory processing in rodents. In humans, it likely contributes to successful complex social networ... Read More about Mice integrate conspecific and contextual information in forming social episodic-like memories under spontaneous recognition task conditions.

Different types of uncertainty in multisensory perceptual decision making (2023)
Journal Article
Aston, S., Nardini, M., & Beierholm, U. (2023). Different types of uncertainty in multisensory perceptual decision making. Philosophical Transactions of the Royal Society B: Biological Sciences, 378(1886), Article 20220349. https://doi.org/10.1098/rstb.2022.0349

Efficient decision-making requires accounting for sources of uncertainty (noise, or variability). Many studies have shown how the nervous system is able to account for perceptual uncertainty (noise, variability) that arises from limitations in its ow... Read More about Different types of uncertainty in multisensory perceptual decision making.

Sensory Augmentation for a Rapid Motor Task in a Multisensory Environment (2023)
Journal Article
Negen, J., Slater, H., & Nardini, M. (2023). Sensory Augmentation for a Rapid Motor Task in a Multisensory Environment. Restorative Neurology and Neuroscience, https://doi.org/10.3233/RNN-221279

Background: Sensory substitution and augmentation systems (SSASy) seek to either replace or enhance existing sensory skills by providing a new route to access information about the world. Tests of such systems have largely been limited to untimed, un... Read More about Sensory Augmentation for a Rapid Motor Task in a Multisensory Environment.

Multisensory perception and decision-making with a new sensory skill (2023)
Journal Article
Negen, J., Bird, L., Slater, H., Thaler, L., & Nardini, M. (2023). Multisensory perception and decision-making with a new sensory skill. Journal of Experimental Psychology: Human Perception and Performance, 49(5), 600-622. https://doi.org/10.1037/xhp0001114

It is clear that people can learn a new sensory skill – a new way of mapping sensory inputs onto world states. It remains unclear how flexibly a new sensory skill can become embedded in multisensory perception and decision-making. To address this, we... Read More about Multisensory perception and decision-making with a new sensory skill.

Pain through the perspective of art and creativity: insights from the Unmasking Pain project (2023)
Journal Article
Johnson, M. I., Chazot, P., Cole, F., Cruickshank, R., Fuller, D., Keyse, C., …Woodall, J. (2023). Pain through the perspective of art and creativity: insights from the Unmasking Pain project. Frontiers in Pain Research, 4, Article 1179116. https://doi.org/10.3389/fpain.2023.1179116

People struggle to tell their story of living with pain and when they do it is articulated in a way that may not be understood, heard or taken seriously. Unmasking Pain is an artist-led project that explored creative approaches to tell stories of lif... Read More about Pain through the perspective of art and creativity: insights from the Unmasking Pain project.

Dynamic resource allocation in spatial working memory during full and partial report tasks (2023)
Journal Article
McAteer, S. M., Ablott, E., McGregor, A., & Smith, D. T. (2023). Dynamic resource allocation in spatial working memory during full and partial report tasks. Journal of Vision, 23(2), Article 10. https://doi.org/10.1167/jov.23.2.10

Serial position effects are well-documented in working memory literature. Studies of spatial short-term memory that rely on binary response; full report tasks tend to report stronger primacy than recency effects. In contrast, studies that utilize a c... Read More about Dynamic resource allocation in spatial working memory during full and partial report tasks.

Frequency matters: how changes in hippocampal theta frequency can influence temporal coding, anxiety-reduction, and memory (2023)
Journal Article
Hines, M., Poulter, S., Douchamps, V., Pibiri, F., McGregor, A., & Lever, C. (2023). Frequency matters: how changes in hippocampal theta frequency can influence temporal coding, anxiety-reduction, and memory. Frontiers in Systems Neuroscience, 16, https://doi.org/10.3389/fnsys.2022.998116

Hippocampal theta frequency is a somewhat neglected topic relative to theta power, phase, coherence, and cross-frequency coupling. Accordingly, here we review and present new data on variation in hippocampal theta frequency, focusing on functional as... Read More about Frequency matters: how changes in hippocampal theta frequency can influence temporal coding, anxiety-reduction, and memory.

Newly learned shape-colour associations show signatures of reliability-weighted averaging without forced fusion or a memory colour effect (2022)
Journal Article
Aston, S., Pattie, C., Graham, R., Slater, H., Beierholm, U., & Nardini, M. (2022). Newly learned shape-colour associations show signatures of reliability-weighted averaging without forced fusion or a memory colour effect. Journal of Vision, 22(13), Article 8. https://doi.org/10.1167/jov.22.13.8

Reliability-weighted averaging of multiple perceptual estimates (or cues) can improve precision. Research suggests that newly-learned statistical associations can be rapidly integrated in this way for efficient decision-making. Yet, it remains unclea... Read More about Newly learned shape-colour associations show signatures of reliability-weighted averaging without forced fusion or a memory colour effect.

Glutamatergic dysfunction leads to a hyper-dopaminergic phenotype through deficits in short-term habituation: a mechanism for aberrant salience (2022)
Journal Article
Panayi, M. C., Boerner, T., Jahans-Price, T., Huber, A., Sprengel, R., Gilmour, G., …Bannerman, D. M. (2022). Glutamatergic dysfunction leads to a hyper-dopaminergic phenotype through deficits in short-term habituation: a mechanism for aberrant salience. Molecular Psychiatry, 28(2023), 579-587. https://doi.org/10.1038/s41380-022-01861-8

Psychosis in disorders like schizophrenia is commonly associated with aberrant salience and elevated striatal dopamine. However, the underlying cause(s) of this hyper-dopaminergic state remain elusive. Various lines of evidence point to glutamatergic... Read More about Glutamatergic dysfunction leads to a hyper-dopaminergic phenotype through deficits in short-term habituation: a mechanism for aberrant salience.

Oculomotor rehearsal in visuospatial working memory (2022)
Journal Article
McAteer, S. M., McGregor, A., & Smith, D. T. (2023). Oculomotor rehearsal in visuospatial working memory. Attention, Perception, and Psychophysics, 85(1), 261-275. https://doi.org/10.3758/s13414-022-02601-4

The neural and cognitive mechanisms of spatial working memory are tightly coupled with the systems that control eye movements, but the precise nature of this coupling is not well understood. It has been argued that the oculomotor system is selectivel... Read More about Oculomotor rehearsal in visuospatial working memory.

Internal Biases Are Linked to Disrupted Cue Combination in Children and Adults" (2022)
Journal Article
Negen, J., Slater, H., Bird, L., & Nardini, M. (2022). Internal Biases Are Linked to Disrupted Cue Combination in Children and Adults". Journal of Vision, 22(12), Article 14. https://doi.org/10.1167/jov.22.12.14

Cue combination describes the use of two sensory cues together to increase perceptual precision. Internal relative bias describes a situation in which two cues to the same state of the world are perceived as signalling different states of the world o... Read More about Internal Biases Are Linked to Disrupted Cue Combination in Children and Adults".

Recent Advances in AI-enabled Automated Medical Diagnosis (2022)
Book
Jiang, R., Zhang, L., Wei, H., Crookes, D., & Chazot, P. (Eds.). (2022). Recent Advances in AI-enabled Automated Medical Diagnosis. Routledge

Developments in deep learning in the past decade have led to phenomenal growth in AI-based automated medical diagnosis, opening a door to a new era of both medical research and medical industry. It is a golden age for researchers involved in the deve... Read More about Recent Advances in AI-enabled Automated Medical Diagnosis.

Machine Learning based Biological Ageing Estimation: A Survey (2022)
Book Chapter
Zhang, Z., Jiang, R., Crookes, D., & Chazot, P. (2022). Machine Learning based Biological Ageing Estimation: A Survey. In R. Jiang, L. Zhang, H.-L. Wei, D. Crookes, & P. Chazot (Eds.), Recent Advances in AI-enabled Automated Medical Diagnosis. Routledge

EEG-based Deep Emotional Diagnosis: A Comparative Study (2022)
Book Chapter
Liu, G., Zhang, Z., Jiang, R., Crookes, D., & Chazot, P. (2022). EEG-based Deep Emotional Diagnosis: A Comparative Study. In R. Jiang, L. Zhang, H. Wei, D. Crookes, & P. Chazot (Eds.), Recent Advances in AI-enabled Automated Medical Diagnosis. Routledge. https://doi.org/10.1201/9781003176121

Emotion is an important part of people's daily life, particularly relevant to the mental health of people. Emotional diagnosis is closely related to the nervous system, which can well reflect people's mental conditions in response to the surrounding... Read More about EEG-based Deep Emotional Diagnosis: A Comparative Study.

Rats use strategies to make object choices in spontaneous object recognition tasks (2022)
Journal Article
Ross, T., & Easton, A. (2022). Rats use strategies to make object choices in spontaneous object recognition tasks. Scientific Reports, 12, Article 16973. https://doi.org/10.1038/s41598-022-21537-1

Rodent spontaneous object recognition (SOR) paradigms are widely used to study the mechanisms of complex memory in many laboratories. Due to the absence of explicit reinforcement in these tasks, there is an underlying assumption that object explorato... Read More about Rats use strategies to make object choices in spontaneous object recognition tasks.

Reinforcement rate and the balance between excitatory and inhibitory learning: insights from deletion of the GluA1 AMPA receptor subunit (2022)
Journal Article
Austen, J. M., Sprengel, R., & Sanderson, D. J. (2022). Reinforcement rate and the balance between excitatory and inhibitory learning: insights from deletion of the GluA1 AMPA receptor subunit. Journal of Experimental Psychology: Animal Learning and Cognition, 48(4), 307-314. https://doi.org/10.1037/xan0000336

Conditioned responding is sensitive to reinforcement rate. This rate-sensitivity is impaired in genetically modified mice that lack the GluA1 subunit of the AMPA receptor. A time-dependent application of the Rescorla–Wagner learning rule can be used... Read More about Reinforcement rate and the balance between excitatory and inhibitory learning: insights from deletion of the GluA1 AMPA receptor subunit.

Developmental changes in colour constancy in a naturalistic object selection task (2022)
Journal Article
Wedge-Roberts, R., Aston, S., Beierholm, U., Kentridge, R., Hurlbert, A., Nardini, M., & Olkkonen, M. (2023). Developmental changes in colour constancy in a naturalistic object selection task. Developmental Science, 26(2), Article e13306. https://doi.org/10.1111/desc.13306

When the illumination falling on a surface changes, so does the reflected light. Despite this, adult observers are good at perceiving surfaces as relatively unchanging – an ability termed colour constancy. Very few studies have investigated colour co... Read More about Developmental changes in colour constancy in a naturalistic object selection task.