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Dr David Doupe's Outputs (2)

Epithelial Stem Cells: Making, Shaping and Breaking the Niche (2022)
Book Chapter
Ferraces-Riegas, P., Galbraith, A. C., & Doupé, D. P. (2022). Epithelial Stem Cells: Making, Shaping and Breaking the Niche. In Advances in Experimental Medicine and Biology. Springer Verlag. https://doi.org/10.1007/5584_2021_686

Epithelial stem cells maintain tissues throughout adult life and are tightly regulated by their microenvironmental niche to balance cell production and loss. These stem cells have been studied extensively as signal-receiving cells, responding to cues... Read More about Epithelial Stem Cells: Making, Shaping and Breaking the Niche.

Toward a Systems Understanding of Signaling Pathway Function (2016)
Book Chapter
Doupé, D. P., & Perrimon, N. (2016). Toward a Systems Understanding of Signaling Pathway Function. In P. M. Wassarman (Ed.), Essays on Developmental Biology, Part B (221-236). Elsevier. https://doi.org/10.1016/bs.ctdb.2015.11.005

A small number of developmental signaling pathways are used repeatedly throughout development in many different contexts. How these pathways interact with each other and the specific cell context to generate a wide range of appropriate responses rema... Read More about Toward a Systems Understanding of Signaling Pathway Function.