Skip to main content

Research Repository

Advanced Search

All Outputs (18)

A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit (2024)
Journal Article
Sun, J., Rojo-Cortés, F., Ulian-Benitez, S., Forero, M. G., Li, G., Singh, D., Wang, X., Cachero, S., Moreira, M., Kavanagh, D., Jefferis, G., Croset, V., & Hidalgo, A. (2024). A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit. eLife, 13, Article RP102222. https://doi.org/10.7554/elife.102222.1

Experience shapes the brain, as neural circuits can be modified by neural stimulation or the lack of it. The molecular mechanisms underlying structural circuit plasticity and how plasticity modifies behaviour, are poorly understood. Subjective experi... Read More about A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit.

Dopaminergic systems create reward seeking despite adverse consequences (2023)
Journal Article
Jovanoski, K. D., Duquenoy, L., Mitchell, J., Kapoor, I., Treiber, C. D., Croset, V., …Waddell, S. (2023). Dopaminergic systems create reward seeking despite adverse consequences. Nature, 623(7986), 356-365. https://doi.org/10.1038/s41586-023-06671-8

Resource-seeking behaviours are ordinarily constrained by physiological needs and threats of danger, and the loss of these controls is associated with pathological reward seeking1. Although dysfunction of the dopaminergic valuation system of the brai... Read More about Dopaminergic systems create reward seeking despite adverse consequences.

Structural circuit plasticity by a neurotrophin with a Toll modifies dopamine-dependent behaviour (2023)
Other
SUN, J., ULIAN-BENITEZ, S., FORERO, M. G., LI, G., SINGH, D., ROJO-CORTES, F. R., WANG, X., CACHERO, S., MOREIRA, M., KAVANAGH, D., JEFFERIS, G. S. X. E., CROSET, V., & HIDALGO, A. Structural circuit plasticity by a neurotrophin with a Toll modifies dopamine-dependent behaviour

Experience shapes the brain, as neural circuits can be modified by neural stimulation or the lack of it. How this modifies behaviour, and the underlying molecular mechanisms, are poorly understood, but could reveal how the brain works, in health and... Read More about Structural circuit plasticity by a neurotrophin with a Toll modifies dopamine-dependent behaviour.

Adult-born neurons add flexibility to hippocampal memories (2023)
Journal Article
Fölsz, O., Trouche, S., & Croset, V. (2023). Adult-born neurons add flexibility to hippocampal memories. Frontiers in Neuroscience, 17, Article 1128623. https://doi.org/10.3389/fnins.2023.1128623

Although most neurons are generated embryonically, neurogenesis is maintained at low rates in specific brain areas throughout adulthood, including the dentate gyrus of the mammalian hippocampus. Episodic-like memories encoded in the hippocampus requi... Read More about Adult-born neurons add flexibility to hippocampal memories.

Gliotransmission of D-serine promotes thirst-directed behaviors in Drosophila (2022)
Journal Article
Park, A., Croset, V., Otto, N., Agarwal, D., Treiber, C. D., Meschi, E., …Waddell, S. (2022). Gliotransmission of D-serine promotes thirst-directed behaviors in Drosophila. Current Biology, 32(18), 3952-3970. https://doi.org/10.1016/j.cub.2022.07.038

Thirst emerges from a range of cellular changes that ultimately motivate an animal to consume water. Although thirst-responsive neuronal signals have been reported, the full complement of brain responses is unclear. Here, we identify molecular and ce... Read More about Gliotransmission of D-serine promotes thirst-directed behaviors in Drosophila.

Publisher Correction: An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing (Nature Communications, (2018), 9, 1, (4252), 10.1038/s41467-018-06453-1) (2020)
Journal Article
Sánchez-Alcañiz, J., Silbering, A., Croset, V., Zappia, G., Sivasubramaniam, A., Abuin, L., …Benton, R. (2020). Publisher Correction: An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing (Nature Communications, (2018), 9, 1, (4252), 10.1038/s41467-018-06453-1). Nature Communications, 11(1), https://doi.org/10.1038/s41467-020-14882-0

A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord (2020)
Journal Article
Allen, A., Neville, M., Birtles, S., Croset, V., Treiber, C., Waddell, S., & Goodwin, S. (2020). A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord. eLife, 9, Article e54074. https://doi.org/10.7554/elife.54074

The Drosophila ventral nerve cord (VNC) receives and processes descending signals from the brain to produce a variety of coordinated locomotor outputs. It also integrates sensory information from the periphery and sends ascending signals to the brain... Read More about A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord.

An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing (2018)
Journal Article
Sánchez-Alcañiz, J., Silbering, A., Croset, V., Zappia, G., Sivasubramaniam, A., Abuin, L., …Benton, R. (2018). An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing. Nature Communications, 9(1), Article 4252. https://doi.org/10.1038/s41467-018-06453-1

Through analysis of the Drosophila ionotropic receptors (IRs), a family of variant ionotropic glutamate receptors, we reveal that most IRs are expressed in peripheral neuron populations in diverse gustatory organs in larvae and adults. We characteris... Read More about An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing.